UBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activity (Q24303456)

hematopoietic stem cell homeostasis

GOA release 2020-03-11

1 reference

Ubiquitin-associated protein 2-like

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Martin Sauvageau

12

0 references

Pierre Thibault

7

object named as

Pierre Thibault

0 references

Guy Sauvageau

15

object named as

Guy Sauvageau

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author name string

Marie-Eve Bordeleau

1

0 references

Romain Aucagne

2

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Jalila Chagraoui

3

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Simon Girard

4

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Nadine Mayotte

5

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Eric Bonneil

6

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Caroline Pabst

8

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Anne Bergeron

9

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Frédéric Barabé

10

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Josée Hébert

11

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Christel Boutonnet

13

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Sylvain Meloche

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes

14

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language of work or name

English

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publication date

9 October 2014

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published in

Blood

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volume

124

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issue

15

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page(s)

2362-9

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

A functional screen to identify novel effectors of hematopoietic stem cell activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Inducible gene targeting in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

An anticlastogenic function for the Polycomb Group gene Bmi1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Polycomb group proteins: multi-faceted regulators of somatic stem cells and cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Bmi1 regulates mitochondrial function and the DNA damage response pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

Identification of small molecules that support human leukemia stem cell activity ex vivo.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4192749

The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25185265

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Enhanced self-renewal of hematopoietic stem cells mediated by the polycomb gene product Bmi-1

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25185265