Bmi1 regulates mitochondrial function and the DNA damage response pathway (Q34017298)

30 July 2017

Bmi1 regulates mitochondrial function and the DNA damage response pathway (English)

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30 July 2017

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18

Toren Finkel

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30 July 2017

13

Ilsa I Rovira

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30 July 2017

Jie Liu

1

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30 July 2017

Liu Cao

2

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30 July 2017

Jichun Chen

3

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30 July 2017

Shiwei Song

4

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30 July 2017

In Hye Lee

5

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30 July 2017

Celia Quijano

6

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30 July 2017

Hongjun Liu

7

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30 July 2017

Keyvan Keyvanfar

8

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30 July 2017

Haoqian Chen

9

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30 July 2017

Long-Yue Cao

10

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30 July 2017

Bong-Hyun Ahn

11

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30 July 2017

Neil G Kumar

12

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30 July 2017

Xiao-Ling Xu

14

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30 July 2017

Maarten van Lohuizen

15

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30 July 2017

Noboru Motoyama

16

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30 July 2017

Chu-Xia Deng

17

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30 July 2017

language of work or name

English

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publication date

29 April 2009

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30 July 2017

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30 July 2017

459

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30 July 2017

7245

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30 July 2017

387-392

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https://scigraph.springernature.com/pub.10.1038/nature08040

30 July 2017

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cites work

shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Advances in measuring cellular bioenergetics using extracellular flux

5 July 2018

1 reference

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Stems cells and the pathways to aging and cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

The common biology of cancer and ageing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Cellular senescence in cancer and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

DNA repair is limiting for haematopoietic stem cells during ageing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Cross-talk between Chk1 and Chk2 in double-mutant thymocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

p16INK4a induces an age-dependent decline in islet regenerative potential

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Differential impact of Ink4a and Arf on hematopoietic stem cells and their bone marrow microenvironment in Bmi1-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Tying the loose ends together in DNA double strand break repair with 53BP1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

DNA repair, genome stability, and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Mitochondria, oxidants, and aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Posterior transformation, neurological abnormalities, and severe hematopoietic defects in mice with a targeted deletion of the bmi-1 proto-oncogene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Direct detection of 8-oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4721521

Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19404261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

c-Kit expression and stem cell factor-induced hematopoietic cell proliferation are up-regulated in aged B6D2F1 mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19404261

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE08040

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference

30 July 2017

1 reference