Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung (Q24303485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

0 references

1 reference

GOA release 2020-03-11

NK2 homeobox 1

1 reference

GOA release 2020-03-11

adenocarcinoma

1 reference

inferred from title

mucinous adenocarcinoma

1 reference

adenocarcinoma of the lung

inferred from title

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

author name string

Yutaka Maeda

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Haiping Hao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

David H Tompkins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Yan Xu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Michael L Mucenski

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Lingling Du

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Angela R Keiser

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Takuya Fukazawa

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Yoshio Naomoto

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Takeshi Nagayasu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Jeffrey A Whitsett

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

12 November 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

17 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

122

1 reference

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17 February 2020

issue

12

1 reference

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17 February 2020

page(s)

4388-4400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma

17 February 2020

cites work

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19 March 2017

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Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells

19 March 2017

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19 March 2017

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Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

19 March 2017

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Characterizing the cancer genome in lung adenocarcinoma

19 March 2017

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Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer

19 March 2017

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SPDEF regulates goblet cell hyperplasia in the airway epithelium

19 March 2017

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19 March 2017

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

19 March 2017

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F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest

19 March 2017

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International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma

19 March 2017

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Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways

19 March 2017

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SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production

19 March 2017

1 reference

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Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1

19 March 2017

1 reference

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Loss of Nkx2.8 deregulates progenitor cells in the large airways and leads to dysplasia

19 March 2017

1 reference

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Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes

19 March 2017

1 reference

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The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary

19 March 2017

1 reference

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Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1

19 March 2017

1 reference

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GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo

19 March 2017

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19 March 2017

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LKB1 modulates lung cancer differentiation and metastasis

7 April 2017

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Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study

26 May 2017

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27 September 2017

1 reference

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Airway epithelial transcription factor NK2 homeobox 1 inhibits mucous cell metaplasia and Th2 inflammation

27 September 2017

1 reference

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Suppression of lung adenocarcinoma progression by Nkx2-1

27 September 2017

1 reference

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Genome-wide transcription factor binding: beyond direct target regulation

27 September 2017

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Abnormalities of the TITF-1 lineage-specific oncogene in NSCLC: implications in lung cancer pathogenesis and prognosis

27 September 2017

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Both gene amplification and allelic loss occur at 14q13.3 in lung cancer

27 September 2017

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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

27 September 2017

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Role of NKX2-1 in N-bis(2-hydroxypropyl)-nitrosamine-induced thyroid adenoma in mice

27 September 2017

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Unique and overlapping gene expression patterns driven by IL-4 and IL-13 in the mouse lung

27 September 2017

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27 September 2017

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Immunohistochemical expression of basic fibroblast growth factor and fibroblast growth factor receptors 1 and 2 in the pathogenesis of lung cancer

27 September 2017

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27 September 2017

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Epithelial NF-kappaB activation promotes urethane-induced lung carcinogenesis

27 September 2017

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FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo

27 September 2017

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27 September 2017

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In vitro susceptibility to the pro-apoptotic effects of TIMP-3 gene delivery translates to greater in vivo efficacy versus gene delivery for TIMPs-1 or -2.

27 September 2017

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MUC5AC mucin gene regulation in pancreatic cancer cells

27 September 2017

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Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors

27 September 2017

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Permissive effects of oxygen on cyclic AMP and interleukin-1 stimulation of surfactant protein A gene expression are mediated by epigenetic mechanisms

27 September 2017

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Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis

27 September 2017

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Thyroid transcription factor 1 is an independent prognostic factor for patients with stage I lung adenocarcinoma

27 September 2017

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Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors

29 November 2018

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Functional FGFR4 Gly388Arg Polymorphism Predicts Prognosis in Lung Adenocarcinoma Patients

29 November 2018

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Foxa2 regulates alveolarization and goblet cell hyperplasia.

29 November 2018

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A random variance model for detection of differential gene expression in small microarray experiments

29 November 2018

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Fas function and tumor progression: use it and lose it.

29 November 2018

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Insulin-like growth factors and cancer

29 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23143308

12 December 2020

inferred from PubMed ID database lookup

Foxa2 programs Th2 cell-mediated innate immunity in the developing lung

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23143308

12 December 2020

inferred from PubMed ID database lookup

Ectopic respiratory epithelial cell differentiation in bronchiolised distal airspaces in idiopathic pulmonary fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23143308

12 December 2020

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Tonicity-dependent induction of Sgk1 expression has a potential role in dehydration-induced natriuresis in rodents.

1 reference

Crossref

https://api.crossref.org/works/10.1172%2FJCI64048

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1172/JCI64048

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23143308%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

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