PML regulates PER2 nuclear localization and circadian function (Q24303487)

PML nuclear body scaffold

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Period circadian clock 2

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Promyelocytic leukemia

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author name string

Takao Miki

1

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Zhixiang Xu

2

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Misty Chen-Goodspeed

3

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Mingguang Liu

4

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Anita Van Oort-Jansen

5

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Michael A Rea

6

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Zhaoyang Zhao

7

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Cheng Chi Lee

8

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Kun-Sang Chang

Biochemical analysis of the canonical model for the mammalian circadian clock

9

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language of work or name

English

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publication date

21 March 2012

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published in

The EMBO Journal

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volume

31

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page(s)

1427-39

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issue

6

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cites work

1 reference

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19 March 2017

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The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

19 March 2017

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SIRT1 regulates circadian clock gene expression through PER2 deacetylation

19 March 2017

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PML regulates p53 stability by sequestering Mdm2 to the nucleolus

19 March 2017

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PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

19 March 2017

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Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence

19 March 2017

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Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

19 March 2017

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The growth suppressor PML represses transcription by functionally and physically interacting with histone deacetylases

19 March 2017

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PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

19 March 2017

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Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2

19 March 2017

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The interferon (IFN)-stimulated gene Sp100 promoter contains an IFN-gamma activation site and an imperfect IFN-stimulated response element which mediate type I IFN inducibility

19 March 2017

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Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins

19 March 2017

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NPAS2: an analog of clock operative in the mammalian forebrain

19 March 2017

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Molecular components of the mammalian circadian clock

19 March 2017

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The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo

19 March 2017

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The role of PML in tumor suppression

19 March 2017

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MPer1 and mper2 are essential for normal resetting of the circadian clock

19 March 2017

1 reference

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Identification of three major sentrinization sites in PML

19 March 2017

1 reference

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Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels

19 March 2017

1 reference

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PML is a direct p53 target that modulates p53 effector functions

19 March 2017

1 reference

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Role of PML in cell growth and the retinoic acid pathway

19 March 2017

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Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

19 March 2017

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

7 April 2017

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Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells

7 April 2017

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mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

7 April 2017

1 reference

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Subcellular distribution of nuclear import-defective isoforms of the promyelocytic leukemia protein

7 April 2017

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Disrupting circadian homeostasis of sympathetic signaling promotes tumor development in mice

27 September 2017

1 reference

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Assembly dynamics of PML nuclear bodies in living cells

27 September 2017

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Cell-cycle regulation and dynamics of cytoplasmic compartments containing the promyelocytic leukemia protein and nucleoporins

27 September 2017

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Involvement of PML nuclear bodies in CBP degradation through the ubiquitin-proteasome pathway

27 September 2017

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Acetylation of PML is involved in histone deacetylase inhibitor-mediated apoptosis

27 September 2017

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27 September 2017

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Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood

27 September 2017

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Sirtuins in aging and disease

27 September 2017

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Phase resetting of the mammalian circadian clock by DNA damage

27 September 2017

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CLOCK-mediated acetylation of BMAL1 controls circadian function

27 September 2017

1 reference

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Expression of the circadian clock genes Per1 and Per2 in sporadic and familial breast tumors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

Functional role of CREB-binding protein in the circadian clock system of Drosophila melanogaster

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

The reversion-inducing cysteine-rich protein with Kazal motifs (RECK) interacts with membrane type 1 matrix metalloproteinase and CD13/aminopeptidase N and modulates their endocytic pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

Circadian gene mPer2 overexpression induces cancer cell apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles

27 September 2017

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Transcription profiling of C/EBP targets identifies Per2 as a gene implicated in myeloid leukemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

A role for PML3 in centrosome duplication and genome stability.

27 September 2017

1 reference

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Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

27 September 2017

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Promyelocytic leukemia protein sensitizes tumor necrosis factor alpha-induced apoptosis by inhibiting the NF-kappaB survival pathway

27 September 2017

1 reference

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Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock

27 September 2017

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Transactivation mechanisms of mouse clock transcription factors, mClock and mArnt3.

27 September 2017

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Dimerization and nuclear entry of mPER proteins in mammalian cells

27 September 2017

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Molecular neurobiology and genetics of circadian rhythms in mammals

27 September 2017

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Suprachiasmatic nucleus: use of 14C-labeled deoxyglucose uptake as a functional marker

27 September 2017

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The tumor suppressor Pml regulates cell fate in the developing neocortex

27 September 2017

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Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

30 May 2018

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Circadian variation in the expression of cell-cycle proteins in human oral epithelium

30 May 2018

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Lesions of the suprachiasmatic nucleus disrupt circadian locomotor rhythms in the mouse.

30 May 2018

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Alternative splicing of PML transcripts predicts coexpression of several carboxy-terminally different protein isoforms

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

Control mechanism of the circadian clock for timing of cell division in vivo.

30 May 2018

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Tumor growth suppression in vivo by overexpression of the circadian component, PER2.

21 January 2018

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Atmospheric carbon dioxide concentrations over the past 60 million years

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2012.1

Phase responses to light pulses in mice lacking functional per or cry genes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FEMBOJ.2012.1

Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

The mPer2 gene encodes a functional component of the mammalian circadian clock.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321181

All's well that ends dead

29 November 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1038/EMBOJ.2012.1

1 reference

201994

201994

1 reference

1 reference

1 reference