MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines (Q24303516)

GOA release 2020-03-11

NK2 homeobox 5

1 reference

GOA release 2020-03-11

leukemia

1 reference

inferred from title

lymphoblastic leukemia

1 reference

5

H G Drexler

0 references

author name string

S Nagel

1

0 references

C Meyer

2

0 references

H Quentmeier

3

0 references

M Kaufmann

4

0 references

R A F MacLeod

A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias

6

0 references

language of work or name

English

0 references

publication date

March 2008

0 references

published in

Leukemia

0 references

volume

22

0 references

issue

3

0 references

page(s)

600-7

0 references

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Deregulation of a Homeobox Gene, HOX11, by the t(10;14) in T Cell Leukemia

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

HOX11, a homeobox-containing T-cell oncogene on human chromosome 10q24

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Foxh1 is essential for development of the anterior heart field

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Myocyte enhancer factor 2C and Nkx2-5 up-regulate each other's expression and initiate cardiomyogenesis in P19 cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Cloning and functional characterization of MEF2D/DAZAP1 and DAZAP1/MEF2D fusion proteins created by a variant t(1;19)(q23;p13.3) in acute lymphoblastic leukemia

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

The transcription factor MEF2C is required for craniofacial development

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

A microarray model system identifies potential new target genes of the proto-oncogene HOX11

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Histone deacetylase 3 interacts with and deacetylates myocyte enhancer factor 2

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Breast cancer cells can evade apoptosis-mediated selective killing by a novel small molecule inhibitor of Bcl-2

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.LEU.2405067

Gene regulatory networks in the evolution and development of the heart

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Homeobox genes in normal and malignant cells.

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Deregulated homeobox gene expression in cancer: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

HOX11L2 expression defines a clinical subtype of pediatric T-ALL associated with poor prognosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Disruption of the RanBP17/Hox11L2 region by recombination with the TCRdelta locus in acute lymphoblastic leukemias with t(5;14)(q34;q11).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 3'-BCL11B enhancers and coregulation by PU.1 and HMGA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Cooperating cancer-gene identification through oncogenic-retrovirus-induced insertional mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Cytogenetic harvesting of commonly used tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Effects of thrombopoietin, interleukin-3 and the kinase inhibitor K-252a on growth and polyploidization of the megakaryocytic cell line M-07e

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

HLXB9 activates IL6 in Hodgkin lymphoma cell lines and is regulated by PI3K signalling involving E2F3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Cardiac myocyte differentiation: the Nkx2.5 and Cripto target genes in P19 clone 6 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

The NK homeodomain transcription factor Tinman is a direct activator of seven-up in the Drosophila dorsal vessel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

D-mef2 is a target for Tinman activation during Drosophila heart development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

PITX2 isoform-specific regulation of atrial natriuretic factor expression: synergism and repression with Nkx2.5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Hand is a direct target of Tinman and GATA factors during Drosophila cardiogenesis and hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Cripto-1: a multifunctional modulator during embryogenesis and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Expression of Pitx2 in stromal cells is required for normal hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Identification of a novel fusion gene in a pre-B acute lymphoblastic leukemia with t(1;19)(q23;p13).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

mef2c is activated directly by myogenic basic helix-loop-helix proteins during skeletal muscle development in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Mef2c is activated directly by Ets transcription factors through an evolutionarily conserved endothelial cell-specific enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

The GATA family (vertebrates and invertebrates).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Nuclear hormone receptors in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Regulation of the MEF2 family of transcription factors by p38

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

The role of molecules that mediate apoptosis in T-cell selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

Beyond the Hox: how widespread is homeobox gene clustering?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

The genesis and evolution of homeobox gene clusters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Promoter demethylation accompanies reactivation of the HOX11 proto-oncogene in leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Comprehensive analysis of homeobox genes in Hodgkin lymphoma cell lines identifies dysregulated expression of HOXB9 mediated via ERK5 signaling and BMI1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

COUP-TF1 antagonizes Nkx2.5-mediated activation of the calreticulin gene during cardiac development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Haploinsufficiency of the cardiac transcription factor Nkx2-5 variably affects the expression of putative target genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

The homeodomain transcription factor NK-4 acts as either a transcriptional activator or repressor and interacts with the p300 coactivator and the Groucho corepressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Expression of GATA-3 during lymphocyte differentiation and mouse embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Positive and negative selection of T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2405067

7 January 2021