Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells (Q24303623)

Discs large MAGUK scaffold protein 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

cell-cell adhesion

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Patrick Laprise

series ordinal

1

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Alain Viel

series ordinal

2

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Nathalie Rivard

series ordinal

3

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language of work or name

English

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publication date

12 March 2004

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published in

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volume

279

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issue

11

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page(s)

10157-66

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cites work

Activation of the protein kinase Akt/PKB by the formation of E-cadherin-mediated cell-cell junctions. Evidence for the association of phosphatidylinositol 3-kinase with the E-cadherin adhesion complex.

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Phosphatidylinositol 3-kinase controls human intestinal epithelial cell differentiation by promoting adherens junction assembly and p38 MAPK activation.

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In vivo analysis of cadherin function in the mouse intestinal epithelium: essential roles in adhesion, maintenance of differentiation, and regulation of programmed cell death

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Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin

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The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

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DLG-1 is a MAGUK similar to SAP97 and is required for adherens junction formation

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Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1

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Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain

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The distribution and function of alternatively spliced insertions in hDlg

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Intestinal epithelial cell differentiation involves activation of p38 mitogen-activated protein kinase that regulates the homeobox transcription factor CDX2.

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RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase

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Hydroxyurea inhibits the transactivation of the HIV-long-terminal repeat (LTR) promoter

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Adherens junctions: new insight into assembly, modulation and function

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Phosphatidylinositol 3-kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation

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Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium

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Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes

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Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation.

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Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation

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Modulation of hemopoietic factor production in relation to endothelial cell aging by interleukin-1 induction

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inferred from DOI database lookup

7 January 2021

based on heuristic

Primary cultures of fully differentiated and pure human intestinal epithelial cells

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inferred from DOI database lookup

7 January 2021

based on heuristic

Differential distribution of digestive enzymes in isolated epithelial cells from developing human fetal small intestine and colon

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