Atypical angiopoietin-like protein that regulates ANGPTL3 (Q24303810)

Angiopoietin like 8

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triglyceride homeostasis

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Angiopoietin-like 8

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author

Eric Boerwinkle

6

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Nick Grishin

4

object named as

Nick V Grishin

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Helen Hobbs

10

object named as

Helen H Hobbs

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Jonathan C. Cohen

9

object named as

Jonathan C Cohen

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author name string

Fabiana Quagliarini

1

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Yan Wang

2

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Julia Kozlitina

3

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Rhonda Hyde

5

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David M Valenzuela

7

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Andrew J Murphy

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

27 November 2012

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published in

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volume

109

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issue

48

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page(s)

19751-6

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cites work

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Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase

19 March 2017

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ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo

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The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms

19 March 2017

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19 March 2017

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Recessive mutations in DOCK6, encoding the guanidine nucleotide exchange factor DOCK6, lead to abnormal actin cytoskeleton organization and Adams-Oliver syndrome

19 March 2017

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19 March 2017

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19 March 2017

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Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice

19 March 2017

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Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue

19 March 2017

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19 March 2017

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ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice

19 March 2017

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Angptl3 regulates lipid metabolism in mice

19 March 2017

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

19 March 2017

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7 April 2017

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Regulation of triglyceride metabolism by Angiopoietin-like proteins

7 April 2017

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Quantitation of serum angiopoietin-like proteins 3 and 4 in a Finnish population sample

27 September 2017

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Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function

27 September 2017

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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.

27 September 2017

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Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL.

27 September 2017

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Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells.

27 September 2017

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Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo.

27 September 2017

1 reference

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SREBPs: transcriptional mediators of lipid homeostasis

27 September 2017

1 reference

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Genetic variation in ANGPTL4 provides insights into protein processing and function

27 September 2017

1 reference

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Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1217552109

Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1217552109

The Dallas Heart Study: a population-based probability sample for the multidisciplinary study of ethnic differences in cardiovascular health.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1217552109

Angptl3-null mice show low plasma lipid concentrations by enhanced lipoprotein lipase activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23150577

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1217552109

1 reference

ADS bibcode

2012PNAS..10919751Q

0 references

1 reference

1 reference

PubMed publication ID

23150577

1 reference