Altered expression levels of IDH2 are involved in the development of colon cancer (Q24305486)

isocitrate dehydrogenase (NADP+) activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Qiang Lv

1

0 references

Shenyang Xing

2

0 references

Zhenxiao Li

3

0 references

Jianhua Li

4

0 references

Pengtao Gong

5

0 references

Xiaofang Xu

6

0 references

LE Chang

7

0 references

Xiaoxia Jin

8

0 references

Feng Gao

9

0 references

Wei Li

10

0 references

Guocai Zhang

11

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Ju Yang

12

0 references

Xichen Zhang

Experimental and Therapeutic Medicine

13

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publication date

November 2012

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published in

1 reference

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

volume

4

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issue

5

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page(s)

801-806

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cites work

1 reference

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19 March 2017

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The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase

19 March 2017

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The consensus coding sequences of human breast and colorectal cancers

19 March 2017

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A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

19 March 2017

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

19 March 2017

1 reference

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Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells.

7 April 2017

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Mitochondrial uncoupling protein 2 expression in colon cancer and its clinical significance

27 September 2017

1 reference

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Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

27 September 2017

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Glioma-derived mutations in IDH: from mechanism to potential therapy

27 September 2017

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Mutant metabolic enzymes are at the origin of gliomas

27 September 2017

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NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences

27 September 2017

1 reference

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NAD+ metabolism in health and disease

27 September 2017

1 reference

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Molecular mechanism of 'mitocan'-induced apoptosis in cancer cells epitomizes the multiple roles of reactive oxygen species and Bcl-2 family proteins.

27 September 2017

1 reference

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Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

27 September 2017

1 reference

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Expression of uncoupling protein-2 in human colon cancer.

27 September 2017

1 reference

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Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

27 September 2017

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The new life of a centenarian: signalling functions of NAD(P).

27 September 2017

1 reference

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Early diagnosis for colorectal cancer in China

27 September 2017

1 reference

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Mitochondrial ROS metabolism: modulation by uncoupling proteins.

27 September 2017

1 reference

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Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism.

27 September 2017

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Mitochondrial respiratory chain inhibitors induce apoptosis.

27 September 2017

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Mutational analysis of IDH1 codon 132 in glioblastomas and other common cancers

30 May 2018

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Roles of NAD(+) / NADH and NADP(+) / NADPH in cell death.

29 November 2018

1 reference

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Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis.

29 November 2018

1 reference

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Silencing of mitochondrial NADP+-dependent isocitrate dehydrogenase by small interfering RNA enhances heat shock-induced apoptosis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3493704

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

29 November 2018

1 reference

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[Epigenetic alterations in colorectal carcinomas and precancerous lesions]

29 November 2018

1 reference

12 December 2020

Regulation of singlet oxygen-induced apoptosis by cytosolic NADP+-dependent isocitrate dehydrogenase

1 reference

12 December 2020

A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells

1 reference

12 December 2020

Use of gene expression profiles to stage concurrent endometrioid tumors of the endometrium and ovary

1 reference

12 December 2020

Somatic mutations of IDH1 and IDH2 in the leukemic transformation of myeloproliferative neoplasms

1 reference

12 December 2020