Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth (Q24305583)

enzyme binding

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Wingless-type MMTV integration site family, member 1

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Frizzled class receptor 8

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Receptor-like tyrosine kinase

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Dishevelled segment polarity protein 1

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Wingless-type MMTV integration site family, member 3A

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Revelations of the RYK receptor

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4

David Baltimore

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author name string

Wange Lu

series ordinal

1

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Vicky Yamamoto

series ordinal

2

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Blanca Ortega

series ordinal

3

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language of work or name

English

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publication date

1 October 2004

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published in

Cell

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volume

119

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page(s)

97-108

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issue

1

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cites work

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Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation

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Phosphorylation of the Drosophila adherens junction protein Armadillo: roles for wingless signal and zeste-white 3 kinase.

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WNT-7a induces axonal remodeling and increases synapsin I levels in cerebellar neurons

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lin-17 mutations of Caenorhabditis elegans disrupt certain asymmetric cell divisions.

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The Drosophila learning and memory gene linotte encodes a putative receptor tyrosine kinase homologous to the human RYK gene product.

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The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

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The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum.

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Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

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XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling

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The Drosophila Wnt, wingless, provides an essential signal for pre- and postsynaptic differentiation

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Expression of receptor tyrosine kinase RYK in developing rat central nervous system.

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WNT-3, Expressed by Motoneurons, Regulates Terminal Arborization of Neurotrophin-3-Responsive Spinal Sensory Neurons

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The Drosophila putative kinase linotte (derailed) prevents central brain axons from converging on a newly described interhemispheric ring.

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The receptor tyrosine kinase gene linotte is required for neuronal pathway selection in the Drosophila mushroom bodies.

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Embryonic expression and activity of doughnut, a second RYK homolog in Drosophila

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You Wnt some, you lose some: oncogenes in the Wnt signaling pathway

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Beta-catenin: a key mediator of Wnt signaling

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Control of beta-catenin stability: reconstitution of the cytoplasmic steps of the wnt pathway in Xenopus egg extracts

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Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled

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A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling

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A new secreted protein that binds to Wnt proteins and inhibits their activities

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The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

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arrow encodes an LDL-receptor-related protein essential for Wingless signalling

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Control of neuronal pathway selection by a Drosophila receptor protein-tyrosine kinase family member

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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Functional interaction of beta-catenin with the transcription factor LEF-1

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Wnt signalling required for expansion of neural crest and CNS progenitors.

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Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

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Axon routing across the midline controlled by the Drosophila Derailed receptor

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Wnt-mediated axon guidance via the Drosophila Derailed receptor

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Differential regulation of midbrain dopaminergic neuron development by Wnt-1, Wnt-3a, and Wnt-5a

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RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs

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Expression of mutated Nck SH2/SH3 adaptor respecifies mesodermal cell fate in Xenopus laevis development

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Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

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Wnt activates the Tak1/Nemo-like kinase pathway

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Lineage-specific requirements of beta-catenin in neural crest development

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Increased neuronal production, enlarged forebrains and cytoarchitectural distortions in beta-catenin overexpressing transgenic mice

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beta-catenin is a target for the ubiquitin-proteasome pathway

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

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Wnt signaling: a common theme in animal development

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Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

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A system for stable expression of short interfering RNAs in mammalian cells

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The promise and perils of Wnt signaling through beta-catenin.

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Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling

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Instructive role of Wnt/beta-catenin in sensory fate specification in neural crest stem cells

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

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Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling

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Mechanisms of Wnt signaling in development

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Reiterated Wnt signaling during zebrafish neural crest development

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Identification of linotte, a new gene affecting learning and memory in Drosophila melanogaster

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