The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex (Q24306032)

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English	The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex	scientific article

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20 February 2020

The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex (English)

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20 February 2020

Transducer of ERBB2, 1

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GOA release 2020-03-11

BTG anti-proliferation factor 2

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GOA release 2020-03-11

negative regulation of translation

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GOA release 2020-03-11

Sebastiaan Winkler

4

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20 February 2020

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Rachel Doidge

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20 February 2020

Saloni Mittal

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20 February 2020

Akhmed Aslam

3

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20 February 2020

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7 December 2012

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20 February 2020

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20 February 2020

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20 February 2020

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20 February 2020

e51331

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20 February 2020

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Creative Commons Attribution 4.0 International

7 December 2012

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0 references

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

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19 March 2017

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

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19 March 2017

Anti-proliferative protein Tob negatively regulates CPEB3 target by recruiting Caf1 deadenylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Quantitative characterization of Tob interactions provides the thermodynamic basis for translation termination-coupled deadenylase regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The Ccr4-NOT deadenylase subunits CNOT7 and CNOT8 have overlapping roles and modulate cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Structural basis for the antiproliferative activity of the Tob-hCaf1 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The BTG2 protein is a general activator of mRNA deadenylation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Mechanism of mRNA deadenylation: evidence for a molecular interplay between translation termination factor eRF3 and mRNA deadenylases

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19 March 2017

Human TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylation

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19 March 2017

Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth

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19 March 2017

Y14 and hUpf3b form an NMD-activating complex

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19 March 2017

Phosphorylation of three regulatory serines of Tob by Erk1 and Erk2 is required for Ras-mediated cell proliferation and transformation

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19 March 2017

Identification of BTG2, an antiproliferative p53-dependent component of the DNA damage cellular response pathway

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The mammalian anti-proliferative BTG/Tob protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Interaction of anti-proliferative protein Tob with poly(A)-binding protein and inducible poly(A)-binding protein: implication of Tob in translational control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Alteration of expression or phosphorylation status of tob, a novel tumor suppressor gene product, is an early event in lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

In search of a function for the TIS21/PC3/BTG1/TOB family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Negative regulation of BMP/Smad signaling by Tob in osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Overexpression of the nerve growth factor-inducible PC3 immediate early gene is associated with growth inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

19 March 2017

Deadenylation of cytoplasmic mRNA by the mammalian Ccr4-Not complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

27 September 2017

The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution

1 reference

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27 September 2017

Evidence providing new insights into TOB-promoted deadenylation and supporting a link between TOB's deadenylation-enhancing and antiproliferative activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

27 September 2017

The Ccr4--not complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

27 September 2017

The structural basis for deadenylation by the CCR4-NOT complex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

27 September 2017

Cytoplasmic deadenylation: regulation of mRNA fate

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27 September 2017

Subunits of the Drosophila CCR4-NOT complex and their roles in mRNA deadenylation.

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27 September 2017

BTG/TOB factors impact deadenylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517456

27 September 2017

TOB suppresses breast cancer tumorigenesis

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27 September 2017

Role for Btg1 and Btg2 in growth arrest of WEHI-231 cells through arginine methylation following membrane immunoglobulin engagement

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27 September 2017

Loss of B-cell translocation gene-2 in estrogen receptor-positive breast carcinoma is associated with tumor grade and overexpression of cyclin d1 protein

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27 September 2017

A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation

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27 September 2017

Phosphorylation of serine 147 of tis21/BTG2/pc3 by p-Erk1/2 induces Pin-1 binding in cytoplasm and cell death

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27 September 2017

A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila

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27 September 2017

Mice lacking a transcriptional corepressor Tob are predisposed to cancer

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27 September 2017

Induction of growth inhibition of 293 cells by downregulation of the cyclin E and cyclin-dependent kinase 4 proteins due to overexpression of TIS21.

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27 September 2017

Deficiency of antiproliferative family protein Ana correlates with development of lung adenocarcinoma

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30 May 2018

Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

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Chapter 23 Tethering Assays to Investigate Nonsense‐Mediated mRNA Decay Activating Proteins

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Multifunctional deadenylase complexes diversify mRNA control

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation and inactivation of Tob contributes to the progression of papillary carcinoma of the thyroid

1 reference

https://pubmed.ncbi.nlm.nih.gov/23236473

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1371/JOURNAL.PONE.0051331

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20 February 2020

2012PLoSO...751331D

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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20 February 2020

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Consolidated OpenCitations Corpus – April 2017

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20 February 2020

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