Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity (Q24307162)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Wenwen Zeng

1

0 references

Zhijian Chen

object named as

Zhijian J Chen

8

1 reference

ORCID Public Data File 2021

Xiaomo Jiang

3

object named as

Xiaomo Jiang

0 references

Anirban Adhikari

6

object named as

Anirban Adhikari

0 references

author name string

Lijun Sun

2

0 references

Xiang Chen

4

0 references

Fajian Hou

5

0 references

Ming Xu

Direct activation of protein kinases by unanchored polyubiquitin chains

7

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language of work or name

English

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publication date

16 April 2010

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published in

Cell

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volume

141

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issue

2

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page(s)

315-30

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cites work

1 reference

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Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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The C-terminal regulatory domain is the RNA 5'-triphosphate sensor of RIG-I

19 March 2017

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

19 March 2017

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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Regulating intracellular antiviral defense and permissiveness to hepatitis C virus RNA replication through a cellular RNA helicase, RIG-I

19 March 2017

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Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

19 March 2017

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

19 March 2017

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Pathogen recognition and innate immunity

19 March 2017

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Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

19 March 2017

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

19 March 2017

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The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin

19 March 2017

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

19 March 2017

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5'-Triphosphate RNA is the ligand for RIG-I

19 March 2017

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

19 March 2017

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Key role of Ubc5 and lysine-63 polyubiquitination in viral activation of IRF3

19 March 2017

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Control of IRF-3 activation by phosphorylation

19 March 2017

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Activation of the IkappaB kinase complex by TRAF6 requires a dimeric ubiquitin-conjugating enzyme complex and a unique polyubiquitin chain

19 March 2017

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Ubiquitin-binding domains

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A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta.

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Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

27 September 2017

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27 September 2017

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Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses

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The death domain superfamily in intracellular signaling of apoptosis and inflammation

27 September 2017

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A nonself RNA pattern: tri-p to panhandle.

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7 January 2021

A ubiquitin ligase complex assembles linear polyubiquitin chains

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Analysis of nondegradative protein ubiquitylation with a monoclonal antibody specific for lysine-63-linked polyubiquitin

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7 January 2021

Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch

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Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation

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7 January 2021

Construct for high-level expression and low misincorporation of lysine for arginine during expression of pET-encoded eukaryotic proteins in Escherichia coli

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10.1016/J.CELL.2010.03.029

Identifiers

DOI

1 reference

163028

163028

1 reference

1 reference

1 reference