Smad inhibition by the Ste20 kinase Misshapen (Q24307319)

GOA release 2020-03-11

protein phosphorylation

1 reference

GOA release 2020-03-11

Satoshi Kaneko

1

Satoshi

Kaneko

1 reference

19 October 2023

Xiaochu Chen

2

Xiaochu

Chen

1 reference

19 October 2023

Peiyuan Lu

3

Peiyuan

Lu

1 reference

19 October 2023

Xiaohao Yao

4

Xiaohao

Yao

1 reference

19 October 2023

Theodore G Wright

5

Theodore G

Wright

1 reference

19 October 2023

Mihir Rajurkar

6

Mihir

Rajurkar

1 reference

19 October 2023

Ken-ichi Kariya

7

Ken-ichi

Kariya

1 reference

19 October 2023

Junhao Mao

8

Junhao

Mao

1 reference

19 October 2023

Y Tony Ip

9

Y Tony

Ip

1 reference

19 October 2023

Lan Xu

10

Lan

Xu

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 October 2023

language of work or name

English

0 references

publication date

5 July 2011

0 references

published in

0 references

volume

108

0 references

issue

27

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page(s)

11127-32

0 references

cites work

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1 reference

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The kinase TNIK is an essential activator of Wnt target genes

19 March 2017

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Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

19 March 2017

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A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase

19 March 2017

1 reference

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The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion

19 March 2017

1 reference

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Physical and functional interactions between type I transforming growth factor beta receptors and Balpha, a WD-40 repeat subunit of phosphatase 2A.

19 March 2017

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

19 March 2017

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Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity

19 March 2017

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The TGF beta receptor activation process: an inhibitor- to substrate-binding switch

19 March 2017

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

19 March 2017

1 reference

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Signal transduction by the TGF-beta superfamily

19 March 2017

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TGFbeta signaling in growth control, cancer, and heritable disorders

19 March 2017

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

19 March 2017

1 reference

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Mechanism of activation of the TGF-beta receptor

19 March 2017

1 reference

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Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

19 March 2017

1 reference

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Specific nucleoporin requirement for Smad nuclear translocation

19 March 2017

1 reference

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Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

27 September 2017

1 reference

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The mammalian family of sterile 20p-like protein kinases

27 September 2017

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Tgf-beta superfamily signaling in embryonic development and homeostasis

27 September 2017

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27 September 2017

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Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads

27 September 2017

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An RNA interference-based screen identifies MAP4K4/NIK as a negative regulator of PPARgamma, adipogenesis, and insulin-responsive hexose transport

27 September 2017

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Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

27 September 2017

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Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

27 September 2017

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TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131379

TGF-beta family signal transduction in Drosophila development: from Mad to Smads.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131379

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131379

Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors

27 September 2017

1 reference

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The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

27 September 2017

1 reference

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Determinants of specificity in TGF-beta signal transduction.

27 September 2017

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Synergistic signaling by two BMP ligands through the SAX and TKV receptors controls wing growth and patterning in Drosophila

27 September 2017

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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3131379

Cyclin-dependent kinases regulate the antiproliferative function of Smads

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104128108

Traf2- and Nck-interacting kinase is essential for Wnt signaling and colorectal cancer growth

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104128108

Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1104128108

The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21690388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

1 reference

https://pubmed.ncbi.nlm.nih.gov/21690388

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1104128108

1 reference

release_e6j4hbyz7zc5nam5xwbtjaj2w4

0 references

0 references

3802212

1 reference

1 reference

3802212

1 reference