L3MBTL1, a histone-methylation-dependent chromatin lock (Q24307503)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061793

RB transcriptional corepressor 1

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H1.4 linker histone, cluster member

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Chromobox 3

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L3MBTL histone methyl-lysine binding protein 2

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L3MBTL1, histone methyl-lysine binding protein

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negative regulation of transcription, DNA-templated

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author

Hediye Erdjument-Bromage

8

object named as

Hediye Erdjument-Bromage

Hediye

Erdjument-Bromage

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9 December 2023

9

Paul Tempst

Paul

Tempst

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9 December 2023

12

Danny Reinberg

Danny

Reinberg

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9 December 2023

1

Patrick Trojer

Patrick

Trojer

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9 December 2023

Guohong Li

2

Guohong

Li

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9 December 2023

Robert J Sims

3

Robert J 3rd

Sims

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9 December 2023

Alejandro Vaquero

4

Alejandro

Vaquero

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9 December 2023

Nagesh Kalakonda

5

Nagesh

Kalakonda

1 reference

9 December 2023

Piernicola Boccuni

6

Piernicola

Boccuni

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9 December 2023

Donghoon Lee

7

Donghoon

Lee

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9 December 2023

Stephen D Nimer

10

Stephen D

Nimer

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9 December 2023

Yuh-Hwa Wang

11

Yuh-Hwa

Wang

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The Drosophila melanogaster tumor suppressor gene lethal(3)malignant brain tumor encodes a proline-rich protein with a novel zinc finger.

9 December 2023

language of work or name

English

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publication date

1 June 2007

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published in

Cell

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volume

129

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issue

5

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page(s)

915-28

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cites work

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

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7 January 2021

Functional characterization of core promoter elements: DPE-specific transcription requires the protein kinase CK2 and the PC4 coactivator

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Histone lysine methylation: a signature for chromatin function

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Methods to identify and functionally analyze factors that specifically recognize histone lysine methylation

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Atomic force microscopy sees nucleosome positioning and histone H1-induced compaction in reconstituted chromatin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Malignant brain tumor repeats: a three-leaved propeller architecture with ligand/peptide binding pockets

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Methods and tips for the purification of human histone methyltransferases

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

1 reference

7 January 2021

Rapid exchange of histone H1.1 on chromatin in living human cells

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Dynamic binding of histone H1 to chromatin in living cells

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Rb targets histone H3 methylation and HP1 to promoters

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Double chromodomains cooperate to recognize the methylated histone H3 tail

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Tudor, MBT and chromo domains gauge the degree of lysine methylation

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Identification of candidate genes on chromosome band 20q12 by physical mapping of translocation breakpoints found in myeloid leukemia cell lines

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Myc pathways provoking cell suicide and cancer

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Nucleosomes, linker DNA, and linker histone form a unique structural motif that directs the higher-order folding and compaction of chromatin

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

The human L(3)MBT polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6)

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Role of the M-loop and reactive center loop domains in the folding and bridging of nucleosome arrays by MENT.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Substrate specificity and kinetic mechanism of mammalian G9a histone H3 methyltransferase

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Scanning chromatin: a new paradigm?

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Chromatin conformation and salt-induced compaction: three-dimensional structural information from cryoelectron microscopy

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Establishment and maintenance of a heterochromatin domain

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Chromatin compaction by a polycomb group protein complex

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Role of nucleosomal cores and histone H1 in regulation of transcription by RNA polymerase II

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Sequence-specific antirepression of histone H1-mediated inhibition of basal RNA polymerase II transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Histone H1 represses estrogen receptor alpha transcriptional activity by selectively inhibiting receptor-mediated transcription initiation

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

Electron microscope visualization of chromatin and other DNA-protein complexes

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https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021

HP1gamma associates with euchromatin and heterochromatin in mammalian nuclei and chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2007.03.048

7 January 2021