Proapoptotic effects of NARC 1 (= PCSK9), the gene encoding a novel serine proteinase (Q24307641)

positive regulation of neuron apoptotic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Brendan Bingham

1

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Ru Shen

2

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Smita Kotnis

3

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C Frederick Lo

4

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Bradley A Ozenberger

5

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Nivedita Ghosh

6

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Jeffrey D Kennedy

7

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J Steven Jacobsen

8

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Jill M Grenier

9

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Peter S DiStefano

10

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Lillian W Chiang

11

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Andrew Wood

The Kex2p proregion is essential for the biosynthesis of an active enzyme and requires a C-terminal basic residue for its function

12

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language of work or name

English

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publication date

1 November 2006

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published in

Cytometry Part A

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volume

69

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page(s)

1123-31

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issue

11

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cites work

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

To die or not to die: an overview of apoptosis and its role in disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Metabolic and genetic analyses of apoptosis in potassium/serum-deprived rat cerebellar granule cells.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

The role of inducible transcription factors in apoptotic nerve cell death

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

An orchestrated gene expression component of neuronal programmed cell death revealed by cDNA array analysis.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Functional characterization of Narc 1, a novel proteinase related to proteinase K

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Mutations in PCSK9 cause autosomal dominant hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Effect of mutations in the PCSK9 gene on the cell surface LDL receptors

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Genetic variants in PCSK9 affect the cholesterol level in Japanese

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Mutations in the PCSK9 gene in Norwegian subjects with autosomal dominant hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Overexpression of PCSK9 accelerates the degradation of the LDLR in a post-endoplasmic reticulum compartment

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Low LDL cholesterol in individuals of African descent resulting from frequent nonsense mutations in PCSK9.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Laser scanning cytometry in the characterization of the proapoptotic effects of transiently transfected genes in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Laser-scanning cytometry: A new instrumentation with many applications

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Protease variants, LDL, and coronary heart disease

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

A spectrum of PCSK9 alleles contributes to plasma levels of low-density lipoprotein cholesterol.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Sequence variations in PCSK9, low LDL, and protection against coronary heart disease

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Expression and localization of PCSK9 in rat hepatic cells

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Biosynthesis and cellular trafficking of the convertase SKI-1/S1P: ectodomain shedding requires SKI-1 activity

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Caspase-dependent and -independent cell death pathways in primary cultures of mesencephalic dopaminergic neurons after neurotoxin treatment.

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Activation of calpain I converts excitotoxic neuron death into a caspase-independent cell death

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

Inhibitors of proprotein convertases

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021

No genetic association between PCSK9 polymorphisms and Alzheimer's disease and plasma cholesterol level in Japanese patients

1 reference

https://api.crossref.org/works/10.1002%2FCYTO.A.20346

7 January 2021