The interferon stimulated gene 12 inactivates vasculoprotective functions of NR4A nuclear receptors (Q24307856)

Exportin 1

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Nuclear receptor subfamily 4 group A member 1

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regulation of protein export from nucleus

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11

Christopher K Glass

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author name string

Nikolina Papac-Milicevic

1

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Johannes M Breuss

2

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Jan Zaujec

3

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Lubos Ryban

4

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Tatiana Plyushch

5

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Gabriel A Wagner

6

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Sabine Fenzl

7

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Paul Dremsek

8

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Muris Cabaravdic

9

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Marianne Steiner

10

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Christoph J Binder

12

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Pavel Uhrin

13

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Bernd R Binder

A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation.

14

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language of work or name

English

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publication date

13 April 2012

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published in

Circulation Research

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volume

110

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issue

8

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page(s)

e50-63

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cites work

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The interferon-induced gene ISG12 is regulated by various cytokines as the gene 6-16 in human cell lines

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Regulation of Nur77 protein turnover through acetylation and deacetylation induced by p300 and HDAC1.

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A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

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Cellular Origins and Thrombogenic Activity of Microparticles Isolated From Human Atherosclerotic Plaques

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Whole-genome microarray analysis identifies up-regulation of Nr4a nuclear receptors in muscle and liver from diet-restricted rats.

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Strain-dependent vascular remodeling phenotypes in inbred mice

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Nuclear receptor coregulators: multiple modes of modification

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Modulation of retinoid signalling through NGF-induced nuclear export of NGFI-B

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FRET-CLSM and double-labeling indirect immunofluorescence to detect close association of proteins in tissue sections

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Cytosporone B is an agonist for nuclear orphan receptor Nur77.

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The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6C- monocytes

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NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism

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Mechanisms of type-I- and type-II-interferon-mediated signalling

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A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53

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Polyethylenimine (PEI) is a simple, inexpensive and effective reagent for condensing and linking plasmid DNA to adenovirus for gene delivery

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The interferon alpha induced protein ISG12 is localized to the nuclear membrane

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Activin and TR3 orphan receptor: two 'atheroprotective' genes as evidenced in dedicated mouse models

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Differential regulation of the transcriptional activity of the orphan nuclear receptor NGFI-B by membrane depolarization and nerve growth factor

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Silencing mediator of retinoid and thyroid hormone receptors and activating signal cointegrator-2 as transcriptional coregulators of the orphan nuclear receptor Nur77.

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The activation function-1 domain of Nur77/NR4A1 mediates trans-activation, cell specificity, and coactivator recruitment

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The AF-1 domain of the orphan nuclear receptor NOR-1 mediates trans-activation, coactivator recruitment, and activation by the purine anti-metabolite 6-mercaptopurine

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Oxidized phospholipids induce expression of human heme oxygenase-1 involving activation of cAMP-responsive element-binding protein.

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Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways

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Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli

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TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77

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Differential display identification of 40 genes with altered expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes

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Dopamine neuron agenesis in Nurr1-deficient mice

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Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3.

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Adrenocortical function and regulation of the steroid 21-hydroxylase gene in NGFI-B-deficient mice

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Unimpaired macrophage differentiation and activation in mice lacking the zinc finger transplantation factor NGFI-A (EGR1).

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Heterodimerization between members of the Nur subfamily of orphan nuclear receptors as a novel mechanism for gene activation

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Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting

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Role of Bone Marrow–Derived Progenitor Cells in Cuff-Induced Vascular Injury in Mice

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Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses

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Protective function of transcription factor TR3 orphan receptor in atherogenesis: decreased lesion formation in carotid artery ligation model in TR3 transgenic mice

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Inhibition of experimental intimal thickening in mice lacking a novel G-protein-coupled receptor

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Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance

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α-Lipoic acid prevents neointimal hyperplasia via induction of p38 mitogen-activated protein kinase/Nur77-mediated apoptosis of vascular smooth muscle cells and accelerates postinjury reendothelialization

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7 January 2021

Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis

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NR4A1 (Nur77) deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis

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Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis

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Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury

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Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility

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Direct binding of Nur77/NAK-1 to the plasminogen activator inhibitor 1 (PAI-1) promoter regulates TNF alpha -induced PAI-1 expression

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GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta

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Vascular endothelial growth factor (VEGF) induces rapid prourokinase (pro-uPA) activation on the surface of endothelial cells

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Urokinase mediates endothelial cell survival via induction of the X-linked inhibitor of apoptosis protein.

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Nuclear envelope transmembrane proteins (NETs) that are up-regulated during myogenesis

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Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77.

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TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen

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Prostaglandin A2 acts as a transactivator for NOR1 (NR4A3) within the nuclear receptor superfamily

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7 January 2021

TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors.

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7 January 2021

TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells.

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7 January 2021

10.1161/CIRCRESAHA.111.258814

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

4867976

4867976

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference