Exportin 1 (Q21111675)

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mammalian protein found in Homo sapiens
  • exportin-1
  • exportin 1 (CRM1 homolog, yeast)
  • chromosome region maintenance 1 protein homolog
  • exportin-1 (required for chromosome region maintenance)
  • chromosome region maintenance 1 homolog
  • XPO1
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Language Label Description Also known as
English
Exportin 1
mammalian protein found in Homo sapiens
  • exportin-1
  • exportin 1 (CRM1 homolog, yeast)
  • chromosome region maintenance 1 protein homolog
  • exportin-1 (required for chromosome region maintenance)
  • chromosome region maintenance 1 homolog
  • XPO1

Statements

molecular function
protein binding
determination method
IPI
29 references
retrieved
8 April 2019
stated in
Two closely related human nuclear export factors utilize entirely distinct export pathways
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of nuclear import and export signals determining the subcellular localization of WD repeat-containing protein 42A (WDR42A)
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
NMDAR signaling facilitates the IPO5-mediated nuclear import of CPEB3
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K.
GOA
curator
UniProt
UniProt protein ID
O14980
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteins
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Biogenesis and nuclear export of ribosomal subunits in higher eukaryotes depend on the CRM1 export pathway
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Structural determinants and mechanism of mammalian CRM1 allostery
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Monoubiquitylation promotes mitochondrial p53 translocation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
CRM1 mediates nuclear-cytoplasmic shuttling of mature microRNAs.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
A human interactome in three quantitative dimensions organized by stoichiometries and abundances
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for assembly and disassembly of the CRM1 nuclear export complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanism
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for leucine-rich nuclear export signal recognition by CRM1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
A new nucleoporin-like protein interacts with both HIV-1 Rev nuclear export signal and CRM-1
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
The nucleoporin-like protein NLP1 (hCG1) promotes CRM1-dependent nuclear protein export
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
retrieved
8 April 2019
stated in
A Competitive binding mechanism between Skp1 and exportin 1 (CRM1) controls the localization of a subset of F-box proteins
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O14980
determination method
IPI
cell component
biological process

Identifiers

MeSH descriptor ID
D000097606
subject named as
Exportin 1 Protein
0 references
 
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