Architectural roles of multiple chromatin insulators at the human apolipoprotein gene cluster (Q24309356)

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Katsuhiko Shirahige

6

0 references

Shinjiro Hino

3

object named as

Shinjiro Hino

0 references

Hiroyuki Aburatani

5

object named as

Hiroyuki Aburatani

0 references

author name string

Tsuyoshi Mishiro

1

0 references

Ko Ishihara

2

0 references

Shuichi Tsutsumi

4

0 references

Yoshikazu Kinoshita

7

0 references

Mitsuyoshi Nakao

The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions

8

0 references

language of work or name

English

0 references

publication date

6 May 2009

0 references

published in

The EMBO Journal

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volume

28

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issue

9

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page(s)

1234-45

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cites work

1 reference

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19 March 2017

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Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

19 March 2017

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An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing

19 March 2017

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Transcriptional repression by the insulator protein CTCF involves histone deacetylases

19 March 2017

1 reference

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The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

19 March 2017

1 reference

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An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

19 March 2017

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High-resolution profiling of histone methylations in the human genome

19 March 2017

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

19 March 2017

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Insulators: exploiting transcriptional and epigenetic mechanisms

19 March 2017

1 reference

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Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development

19 March 2017

1 reference

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CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

19 March 2017

1 reference

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CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Transcriptional regulation of the human apolipoprotein genes

19 March 2017

1 reference

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Physical and functional interaction between two pluripotent proteins, the Y-box DNA/RNA-binding factor, YB-1, and the multivalent zinc finger factor, CTCF

19 March 2017

1 reference

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CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

19 March 2017

1 reference

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Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

19 March 2017

1 reference

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Splitting the chromosome: cutting the ties that bind sister chromatids

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

A novel sequence-specific DNA binding protein which interacts with three regularly spaced direct repeats of the CCCTC-motif in the 5'-flanking sequence of the chicken c-myc gene

19 March 2017

1 reference

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CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

19 March 2017

1 reference

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CTCF-dependent chromatin insulator is linked to epigenetic remodeling

19 March 2017

1 reference

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An evolutionarily conserved putative insulator element near the 3' boundary of the imprinted Igf2/H19 domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Cohesins functionally associate with CTCF on mammalian chromosome arms

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Cohesin mediates transcriptional insulation by CCCTC-binding factor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Quantitative analysis of chromosome conformation capture assays (3C-qPCR).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Roles of the sister chromatid cohesion apparatus in gene expression, development, and human syndromes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Genetic susceptibility to coronary artery disease: from promise to progress.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The role of chromatin structure in regulating the expression of clustered genes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The APOA1/C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

An insulator blocks spreading of histone acetylation and interferes with RNA polymerase II transfer between an enhancer and gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The insulator binding protein CTCF associates with the nuclear matrix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Insulators: many functions, many mechanisms.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Insulators and boundaries: versatile regulatory elements in the eukaryotic genome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Structural and functional conservation at the boundaries of the chicken beta-globin domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Control of apolipoprotein AI gene expression through synergistic interactions between hepatocyte nuclear factors 3 and 4.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

A treasure trove for lipoprotein biology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Associations of the apolipoprotein A1/C3/A4/A5 gene cluster with triglyceride and HDL cholesterol levels in women with type 2 diabetes

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Hepatocyte nuclear factor-4alpha regulates the human apolipoprotein AV gene: identification of a novel response element and involvement in the control by peroxisome proliferator-activated receptor-gamma coactivator-1alpha, AMP-activated protein kina

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

The expression of intact and mutant human apoAI/CIII/AIV/AV gene cluster in transgenic mice.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

A Loss of Insulin-like Growth Factor-2 Imprinting Is Modulated by CCCTC-binding Factor Down-regulation at Senescence in Human Epithelial Cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

DNA binding sites for putative methylation boundaries in the unmethylated region of the BRCA1 promoter.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

3C technology: analyzing the spatial organization of genomic loci in vivo.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Two insulators are not better than one.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2683055

Familial apolipoprotein A-I, C-III, and A-IV deficiency and premature atherosclerosis due to deletion of a gene complex on chromosome 11

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19322193

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Transcriptional regulation of the human apolipoprotein genes

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.81