Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair (Q24309357)

GOA release 2020-03-11

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15

Tiziana Bruno

Tiziana

Bruno

1 reference

19 October 2023

12

Marisa S Bartolomei

Marisa S

Bartolomei

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19 October 2023

Irwin Davidson

21

Irwin

Davidson

2 references

ORCID Public Data File 2021

19 October 2023

Salvatore Cortellino

1

Salvatore

Cortellino

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19 October 2023

Jinfei Xu

2

Jinfei

Xu

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19 October 2023

Mara Sannai

3

Mara

Sannai

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19 October 2023

Robert Moore

4

Robert

Moore

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19 October 2023

Elena Caretti

5

Elena

Caretti

1 reference

19 October 2023

Antonio Cigliano

6

Antonio

Cigliano

1 reference

19 October 2023

Madeleine Le Coz

7

Madeleine

Le Coz

1 reference

19 October 2023

Karthik Devarajan

8

Karthik

Devarajan

1 reference

19 October 2023

Andy Wessels

9

Andy

Wessels

1 reference

19 October 2023

Dianne Soprano

10

Dianne

Soprano

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19 October 2023

Lara K Abramowitz

11

Lara K

Abramowitz

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19 October 2023

Florian Rambow

13

Florian

Rambow

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19 October 2023

Maria Rosaria Bassi

14

Maria Rosaria

Bassi

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19 October 2023

Maurizio Fanciulli

16

Maurizio

Fanciulli

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19 October 2023

Catherine Renner

17

Catherine

Renner

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19 October 2023

Andres J Klein-Szanto

18

Andres J

Klein-Szanto

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19 October 2023

Yoshihiro Matsumoto

19

Yoshihiro

Matsumoto

1 reference

19 October 2023

Dominique Kobi

20

Dominique

Kobi

1 reference

19 October 2023

Christophe Alberti

22

Christophe

Alberti

1 reference

19 October 2023

Lionel Larue

23

Lionel

Larue

1 reference

19 October 2023

Alfonso Bellacosa

24

Alfonso

Bellacosa

1 reference

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

19 October 2023

language of work or name

English

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publication date

8 July 2011

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published in

Cell

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volume

146

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issue

1

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page(s)

67-79

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Sequential DNA methylation of the Nanog and Oct-4 upstream regions in human NT2 cells during neuronal differentiation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

T:G mismatch-specific thymine-DNA glycosylase potentiates transcription of estrogen-regulated genes through direct interaction with estrogen receptor alpha

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Epigenetic reprogramming in mammalian development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Glucocorticoid-induced DNA demethylation and gene memory during development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Extensive brain hemorrhage and embryonic lethality in a mouse null mutant of CREB-binding protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Gadd45 family proteins are coactivators of nuclear hormone receptors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The history of cancer epigenetics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Induction of Tumors in Mice by Genomic Hypomethylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Cancer epigenetics comes of age

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Active DNA demethylation: many roads lead to Rome.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA demethylation in hormone-induced transcriptional derepression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

CpG islands--'a rough guide'.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Active DNA demethylation and DNA repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA demethylation by DNA repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The colorful history of active DNA demethylation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

GADD45A does not promote DNA demethylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Cyclical DNA methylation of a transcriptionally active promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Pioneer factor interactions and unmethylated CpG dinucleotides mark silent tissue-specific enhancers in embryonic stem cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Genetic and epigenetic regulators of pluripotency

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Association of Dnmt3a and thymine DNA glycosylase links DNA methylation with base-excision repair.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The enigmatic thymine DNA glycosylase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Active cytosine demethylation triggered by a nuclear receptor involves DNA strand breaks.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DEMETER and REPRESSOR OF SILENCING 1 encode 5-methylcytosine DNA glycosylases.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DEMETER DNA glycosylase establishes MEDEA polycomb gene self-imprinting by allele-specific demethylation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Function of retinoid nuclear receptors: lessons from genetic and pharmacological dissections of the retinoic acid signaling pathway during mouse embryogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Decreased embryonic retinoic acid synthesis results in a DiGeorge syndrome phenotype in newborn mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Characterization of the substrate specificity of a human 5-hydroxymethyluracil glycosylase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Nuclear cloning and epigenetic reprogramming of the genome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Active demethylation of the paternal genome in the mouse zygote

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complex

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

The essentials of DNA methylation

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA methylation: a molecular lock

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

DNA methylation directs a time-dependent repression of transcription initiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Establishment and maintenance of H19 imprinting in the germline and preimplantation embryo.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Inactivation of imprinted genes induced by cellular stress and tumorigenesis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Retinoic acid receptors interact physically and functionally with the T:G mismatch-specific thymine-DNA glycosylase

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3230223

Mitochondria and the death of oocytes

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21722948

12 December 2020

inferred from PubMed ID database lookup

DNA methylation in eukaryotes

1 reference

https://pubmed.ncbi.nlm.nih.gov/21722948

12 December 2020

inferred from PubMed ID database lookup

Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Comparison of RNA amplification methods and chip platforms for microarray analysis of samples processed by laser capture microdissection

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Demethylation of the zygotic paternal genome

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Adenovirus DNA replication in vitro

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

MED1, a novel human methyl-CpG-binding endonuclease, interacts with DNA mismatch repair protein MLH1

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Differential role of homologous positively charged amino acid residues for ligand binding in retinoic acid receptor alpha compared with retinoic acid receptor beta

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Summaries of Affymetrix GeneChip probe level data

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https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2011.06.020

7 January 2021

10.1016/J.CELL.2011.06.020

Identifiers

DOI

1 reference

release_poj4djypjfg2tdycil7vlbfkmm

Fatcat ID

0 references

1 reference

1 reference

1 reference