Structure of class B GPCR corticotropin-releasing factor receptor 1 (Q24309523)

GOA release 2020-03-11

author name string

Kaspar Hollenstein

1

0 references

James Kean

2

0 references

Andrea Bortolato

3

0 references

Robert K Y Cheng

4

0 references

Andrew S Doré

5

0 references

Ali Jazayeri

6

0 references

Robert M Cooke

7

0 references

Malcolm Weir

8

0 references

Fiona H Marshall

Structure of the human smoothened receptor bound to an antitumour agent

9

0 references

language of work or name

English

0 references

publication date

25 July 2013

0 references

published in

Nature

0 references

volume

499

0 references

issue

7459

0 references

page(s)

438-43

0 references

cites work

1 reference

Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1

20 April 2017

1 reference

Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

20 April 2017

1 reference

Molecular recognition of parathyroid hormone by its G protein-coupled receptor

20 April 2017

1 reference

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism

20 April 2017

1 reference

Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

20 April 2017

1 reference

Molecular basis for negative regulation of the glucagon receptor

20 April 2017

1 reference

Diversity and modularity of G protein-coupled receptor structures

20 April 2017

1 reference

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

20 April 2017

1 reference

Crystal structure of the β2 adrenergic receptor-Gs protein complex

20 April 2017

1 reference

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

20 April 2017

1 reference

Protein homology detection by HMM-HMM comparison

20 April 2017

1 reference

Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes

20 April 2017

1 reference

20 April 2017

1 reference

Overview of the CCP4 suite and current developments

20 April 2017

1 reference

Crystal structure of a lipid G protein-coupled receptor

20 April 2017

1 reference

Phasercrystallographic software

20 April 2017

1 reference

Features and development of Coot

20 April 2017

1 reference

PHENIX: a comprehensive Python-based system for macromolecular structure solution

20 April 2017

1 reference

REFMAC5 for the refinement of macromolecular crystal structures

20 April 2017

1 reference

MolProbity: all-atom structure validation for macromolecular crystallography

20 April 2017

1 reference

Structural diversity of G protein-coupled receptors and significance for drug discovery

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

The structure and function of G-protein-coupled receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Crystallizing membrane proteins using lipidic mesophases

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Molecular signatures of G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

The use of GPCR structures in drug design.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

CRF and CRF receptors: role in stress responsivity and other behaviors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Corticotropin releasing hormone--a GPCR drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

2-aryloxy-4-alkylaminopyridines: discovery of novel corticotropin-releasing factor 1 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Allosteric ligands for the corticotropin releasing factor type 1 receptor modulate conformational states involved in receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Progress in corticotropin-releasing factor-1 antagonist development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Conformational thermostabilization of the beta1-adrenergic receptor in a detergent-resistant form

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Thermostabilization of the neurotensin receptor NTS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Point mutations in the first and third intracellular loops of the glucagon-like peptide-1 receptor alter intracellular signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Constitutive activity of glucagon receptor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Single amino acid residue determinants of non-peptide antagonist binding to the corticotropin-releasing factor1 (CRF1) receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

The properties of thermostabilised G protein-coupled receptors (StaRs) and their use in drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Fluorescence-detection size-exclusion chromatography for precrystallization screening of integral membrane proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Automated real-space refinement of protein structures using a realistic backbone move set.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12357

Corticotropin releasing factor receptors and their ligand family

21 January 2018

1 reference

12 December 2020

Transmembrane residues of the parathyroid hormone (PTH)/PTH-related peptide receptor that specifically affect binding and signaling by agonist ligands

1 reference

12 December 2020

Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop

1 reference

12 December 2020

A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors.

1 reference

12 December 2020

Evolution of exenatide as a diabetes therapeutic

1 reference

12 December 2020

1 reference

12 December 2020

Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis.

1 reference

12 December 2020