Structural diversity of G protein-coupled receptors and significance for drug discovery (Q29616716)

Europe PubMed Central

title

Structural diversity of G protein-coupled receptors and significance for drug discovery (English)

1 reference

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G protein-coupled receptor

30 April 2017

main subject

0 references

1 reference

2

Schiöth HB

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30 April 2017

Lagerström MC

1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

30 April 2017

language of work or name

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30 April 2017

publication date

April 2008

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Nature Reviews Drug Discovery

30 April 2017

published in

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

30 April 2017

volume

7

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

30 April 2017

issue

4

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

30 April 2017

page(s)

339-57

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Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin

30 April 2017

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The structure of bovine rhodopsin

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Rhodopsin's protein and carbohydrate structure: selected aspects.

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Historical review: a brief history and personal retrospective of seven-transmembrane receptors

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Cloning of the gene and cDNA for mammalian beta-adrenergic receptor and homology with rhodopsin

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Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction

31 March 2020

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cDNA cloning of bovine substance-K receptor through oocyte expression system.

31 March 2020

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Molecular cloning of the thyrotropin receptor

31 March 2020

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Design of a discriminating fingerprint for G-protein-coupled receptors

31 March 2020

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Fingerprinting G-protein-coupled receptors

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International Union of Pharmacology. XLVI. G protein-coupled receptor list.

31 March 2020

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

31 March 2020

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Initial sequencing and analysis of the human genome

31 March 2020

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The Sequence of the Human Genome

31 March 2020

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The G protein-coupled receptor repertoires of human and mouse

31 March 2020

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The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

31 March 2020

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A novel family of mammalian taste receptors

31 March 2020

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A family of candidate taste receptors in human and mouse

31 March 2020

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The repertoire of G-protein-coupled receptors in fully sequenced genomes

31 March 2020

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The G protein-coupled receptor subset of the rat genome

31 March 2020

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The G protein-coupled receptor subset of the chicken genome

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Crystal structure of rhodopsin: A G protein-coupled receptor

31 March 2020

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Locating ligand-binding sites in 7TM receptors by protein engineering.

31 March 2020

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A physicogenetic method to assign ligand-binding relationships between 7TM receptors

31 March 2020

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

31 March 2020

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Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

31 March 2020

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Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

31 March 2020

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Cloning and characterization of human protease-activated receptor 4

31 March 2020

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Molecular cloning and functional expression of the gene encoding the human proteinase-activated receptor 2

31 March 2020

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Protease-activated receptor 3 is a second thrombin receptor in humans

31 March 2020

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The three subfamilies of leucine-rich repeat-containing G protein-coupled receptors (LGR): identification of LGR6 and LGR7 and the signaling mechanism for LGR7

31 March 2020

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Activation of orphan receptors by the hormone relaxin

31 March 2020

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Structure of human follicle-stimulating hormone in complex with its receptor

31 March 2020

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GPCR agonists and antagonists in the clinic

31 March 2020

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A chemogenomic analysis of the transmembrane binding cavity of human G-protein-coupled receptors

31 March 2020

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The 7 TM G-protein-coupled receptor target family

31 March 2020

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Structural basis of beta-adrenergic receptor function.

31 March 2020

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The forgotten serine. A critical role for Ser-2035.42 in ligand binding to and activation of the beta 2-adrenergic receptor.

31 March 2020

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Sequential binding of agonists to the beta2 adrenoceptor. Kinetic evidence for intermediate conformational states

31 March 2020

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Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

31 March 2020

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Chemokines, chemokine receptors and small-molecule antagonists: recent developments

31 March 2020

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Orphan GPCRs and their ligands

31 March 2020

1 reference

Deorphanization of a G protein-coupled receptor for oleoylethanolamide and its use in the discovery of small-molecule hypophagic agents

31 March 2020

1 reference

Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives

31 March 2020

1 reference

Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

31 March 2020

1 reference

Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells

31 March 2020

1 reference

Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35

31 March 2020

1 reference

The orphan GPCR GPR87 was deorphanized and shown to be a lysophosphatidic acid receptor

31 March 2020

1 reference

Comprehensive repertoire and phylogenetic analysis of the G protein-coupled receptors in human and mouse

31 March 2020

1 reference

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

31 March 2020

1 reference

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

31 March 2020

1 reference

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

31 March 2020

1 reference

GABA(B2) is essential for g-protein coupling of the GABA(B) receptor heterodimer

31 March 2020

1 reference

Putative mammalian taste receptors: a class of taste-specific GPCRs with distinct topographic selectivity

31 March 2020

1 reference

Human receptors for sweet and umami taste

31 March 2020

1 reference

An amino-acid taste receptor

31 March 2020

1 reference

Mammalian sweet taste receptors

31 March 2020

1 reference

Identification of a novel member of the T1R family of putative taste receptors

31 March 2020

1 reference

Selective amplification and cloning of four new members of the G protein-coupled receptor family

31 March 2020

1 reference

A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

31 March 2020

1 reference

Expression of members of the putative olfactory receptor gene family in mammalian germ cells

31 March 2020

1 reference

The human repertoire of odorant receptor genes and pseudogenes

31 March 2020

1 reference

The human olfactory receptor gene family

31 March 2020

1 reference

Evolution of olfactory receptor genes in the human genome

31 March 2020

1 reference

The human olfactory receptor repertoire

31 March 2020

1 reference

The olfactory receptor gene superfamily: data mining, classification, and nomenclature

31 March 2020

1 reference

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

31 March 2020

1 reference

Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons

31 March 2020

1 reference

Molecular mechanisms underlying differential odor responses of a mouse olfactory receptor

31 March 2020

1 reference

Amino-acid changes acquired during evolution by olfactory receptor 912-93 modify the specificity of odorant recognition

31 March 2020

1 reference

Analysis of the molecular basis for octanal interactions in the expressed rat 17 olfactory receptor

31 March 2020

1 reference

Combinatorial receptor codes for odors

31 March 2020

1 reference

Identification of a testicular odorant receptor mediating human sperm chemotaxis

31 March 2020

1 reference

Identification of specific ligands for orphan olfactory receptors. G protein-dependent agonism and antagonism of odorants

31 March 2020

1 reference

Identification of ligands for olfactory receptors by functional expression of a receptor library

31 March 2020

1 reference

Functional characterization of two human olfactory receptors expressed in the baculovirus Sf9 insect cell system.

31 March 2020

1 reference

The sense of smell: genomics of vertebrate odorant receptors

31 March 2020

1 reference

Family-B G-protein-coupled receptors

31 March 2020

1 reference

Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1

31 March 2020

1 reference

The N-terminal fragment of human parathyroid hormone receptor 1 constitutes a hormone binding domain and reveals a distinct disulfide pattern

31 March 2020

1 reference

In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor

31 March 2020

1 reference

NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor

31 March 2020

1 reference

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

31 March 2020

1 reference

Juxtamembrane region of the amino terminus of the corticotropin releasing factor receptor type 1 is important for ligand interaction

31 March 2020

1 reference

Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling

31 March 2020

1 reference

Spatial proximity between a photolabile residue in position 19 of salmon calcitonin and the amino terminus of the human calcitonin receptor

31 March 2020

1 reference

Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor

31 March 2020

1 reference

Importance of the amino terminus in secretin family G protein-coupled receptors. Intrinsic photoaffinity labeling establishes initial docking constraints for the calcitonin receptor

31 March 2020

1 reference

Spatial approximation between the amino terminus of a peptide agonist and the top of the sixth transmembrane segment of the secretin receptor.

31 March 2020

1 reference

Glucagon-like peptide 1 and its derivatives in the treatment of diabetes.

31 March 2020

1 reference

LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors

31 March 2020

1 reference

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors

31 March 2020

1 reference

EMR1, an unusual member in the family of hormone receptors with seven transmembrane segments

31 March 2020

1 reference

alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor

31 March 2020

1 reference

Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site [...]

31 March 2020

1 reference

Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif

31 March 2020

1 reference

ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily

31 March 2020

1 reference

Molecular analysis of the epidermal growth factor-like short consensus repeat domain-mediated protein-protein interactions: dissection of the CD97-CD55 complex.

31 March 2020

1 reference

Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors

31 March 2020

1 reference

Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association

31 March 2020

1 reference

The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans

31 March 2020

1 reference

Human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 is a new member of the EGF-TM7 family that recognizes a ligand on human macrophages and activated neutrophils

31 March 2020

1 reference

EMR4, a novel epidermal growth factor (EGF)-TM7 molecule up-regulated in activated mouse macrophages, binds to a putative cellular ligand on B lymphoma cell line A20

31 March 2020

1 reference

The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF)

31 March 2020

1 reference

Characterization of the CD55 (DAF)-binding site on the seven-span transmembrane receptor CD97

31 March 2020

1 reference

GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis

31 March 2020

1 reference

GPR56, a novel secretin-like human G-protein-coupled receptor gene

31 March 2020

1 reference

alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.

31 March 2020

1 reference

Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (CIRL) deletion mutants

31 March 2020

1 reference

Celsr1, a neural-specific gene encoding an unusual seven-pass transmembrane receptor, maps to mouse chromosome 15 and human chromosome 22qter

31 March 2020

1 reference

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening

31 March 2020

1 reference

Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

31 March 2020

1 reference

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

31 March 2020

1 reference

A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis

31 March 2020

1 reference

Cloning of a human epididymis-specific mRNA, HE6, encoding a novel member of the seven transmembrane-domain receptor superfamily

31 March 2020

1 reference

Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1)

31 March 2020

1 reference

31 March 2020

1 reference

Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions

31 March 2020

1 reference

There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini

31 March 2020

1 reference

Two novel genes, Gpr113, which encodes a family 2 G-protein-coupled receptor, and Trcg1, are selectively expressed in taste receptor cells

31 March 2020

1 reference

Ig-hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs

31 March 2020

1 reference

Cleavage of Ig-Hepta at a "SEA" module and at a conserved G protein-coupled receptor proteolytic site

31 March 2020

1 reference

Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins

31 March 2020

1 reference

Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system

31 March 2020

1 reference

Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice

31 March 2020

1 reference

Identification of novel splice variants of Adhesion G protein-coupled receptors

31 March 2020

1 reference

The evolutionary history and tissue mapping of GPR123: specific CNS expression pattern predominantly in thalamic nuclei and regions containing large pyramidal cells

31 March 2020

1 reference

The gene repertoire and the common evolutionary history of glutamate, pheromone (V2R), taste(1) and other related G protein-coupled receptors

31 March 2020

1 reference

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

31 March 2020

1 reference

The ligand-binding domain in metabotropic glutamate receptors is related to bacterial periplasmic binding proteins

31 March 2020

1 reference

Conservation of the ligand recognition site of metabotropic glutamate receptors during evolution.

31 March 2020

1 reference

Structures of the extracellular regions of the group II/III metabotropic glutamate receptors

31 March 2020

1 reference

The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain

31 March 2020

1 reference

Cloning and characterization of an extracellular Ca(2+)-sensing receptor from bovine parathyroid

31 March 2020

1 reference

31 March 2020

1 reference

Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G-protein-coupled receptor

31 March 2020

1 reference

Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor

31 March 2020

1 reference

Molecular diversity of glutamate receptors and implications for brain function

31 March 2020

1 reference

Structural basis for a Ca2+-sensing function of the metabotropic glutamate receptors.

31 March 2020

1 reference

L-amino acid sensing by the extracellular Ca2+-sensing receptor

31 March 2020

1 reference

Different functional roles of T1R subunits in the heteromeric taste receptors

31 March 2020

1 reference

Coupling of agonist binding to effector domain activation in metabotropic glutamate-like receptors

31 March 2020

1 reference

NCD3G: a novel nine-cysteine domain in family 3 GPCRs

31 March 2020

1 reference

Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors

31 March 2020

1 reference

Autosomal dominant hypocalcemia: a novel activating mutation (E604K) in the cysteine-rich domain of the calcium-sensing receptor

31 March 2020

1 reference

The cysteine-rich region of T1R3 determines responses to intensely sweet proteins

31 March 2020

1 reference

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

31 March 2020

1 reference

Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2.

31 March 2020

1 reference

Mutagenesis and modeling of the GABAB receptor extracellular domain support a venus flytrap mechanism for ligand binding

31 March 2020

1 reference

Structure-function relationships of the complement components

31 March 2020

1 reference

Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit.

31 March 2020

1 reference

Locking the dimeric GABA(B) G-protein-coupled receptor in its active state.

31 March 2020

1 reference

The calcimimetic cinacalcet normalizes serum calcium in subjects with primary hyperparathyroidism

31 March 2020

1 reference

Mutational Analysis and Molecular Modeling of the Binding Pocket of the Metabotropic Glutamate 5 Receptor Negative Modulator 2-Methyl-6-(phenylethynyl)-pyridine

31 March 2020

1 reference

Allosteric modulators of group I metabotropic glutamate receptors: novel subtype-selective ligands and therapeutic perspectives.

31 March 2020

1 reference

Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain

31 March 2020

1 reference

Modeling and Mutagenesis of the Binding Site of Calhex 231, a Novel Negative Allosteric Modulator of the Extracellular Ca2+-sensing Receptor

31 March 2020

1 reference

Positive allosteric modulators of metabotropic glutamate 1 receptor: characterization, mechanism of action, and binding site

31 March 2020

1 reference

Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.

31 March 2020

1 reference

Lactisole interacts with the transmembrane domains of human T1R3 to inhibit sweet taste.

31 March 2020

1 reference

The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor

31 March 2020

1 reference

Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses.

31 March 2020

1 reference

Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids

31 March 2020

1 reference

Pharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations

31 March 2020

1 reference

Molecular cloning and characterisation of a novel GABAB-related G-protein coupled receptor

31 March 2020

1 reference

Molecular cloning and characterization of a novel retinoic acid-inducible gene that encodes a putative G protein-coupled receptor

31 March 2020

1 reference

Cloning and characterization of a human orphan family C G-protein coupled receptor GPRC5D

31 March 2020

1 reference

Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain

31 March 2020

1 reference

Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C).

31 March 2020

1 reference

Complete sequencing and characterization of 21,243 full-length human cDNAs

31 March 2020

1 reference

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

31 March 2020

1 reference

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled

31 March 2020

1 reference

A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23

31 March 2020

1 reference

A human homologue of the Drosophila polarity gene frizzled has been identified and mapped to 17q21.1

31 March 2020

1 reference

Molecular cloning of human Frizzled-6

31 March 2020

1 reference

Identification, gene structure, and expression of human frizzled-3 (FZD3)

31 March 2020

1 reference

Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7

31 March 2020

1 reference

Molecular cloning and characterization of human Frizzled-4 on chromosome 11q14-q21.

31 March 2020

1 reference

Molecular cloning of Frizzled-10, a novel member of the Frizzled gene family

31 March 2020

1 reference

A new member of the frizzled family from Drosophila functions as a Wingless receptor

31 March 2020

1 reference

Sonic hedgehog signaling by the patched-smoothened receptor complex

31 March 2020

1 reference

Interaction of Wnt and a Frizzled homologue triggers G-protein-linked phosphatidylinositol signalling

31 March 2020

1 reference

Activation of heterotrimeric G proteins by Smoothened

31 March 2020

1 reference

Frizzled proteins constitute a novel family of G protein-coupled receptors, most closely related to the secretin family

31 March 2020

1 reference

Frizzled receptor dimerization is sufficient to activate the Wnt/beta-catenin pathway.

31 March 2020

1 reference

Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains

31 March 2020

1 reference

Evidence that the cysteine-rich domain of Drosophila Frizzled family receptors is dispensable for transducing Wingless

31 March 2020

1 reference

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

31 March 2020

1 reference

Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy

31 March 2020

1 reference

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

31 March 2020

1 reference

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

31 March 2020

1 reference

Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila

31 March 2020

1 reference

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

31 March 2020

1 reference

Small molecule modulation of Smoothened activity

31 March 2020

1 reference

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

31 March 2020

1 reference

Therapeutic potential of antibodies against FZD 10, a cell-surface protein, for synovial sarcomas

31 March 2020

1 reference

Adaptive diversification of bitter taste receptor genes in Mammalian evolution

31 March 2020

1 reference

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates

31 March 2020

1 reference

Identification and characterization of human taste receptor genes belonging to the TAS2R family

31 March 2020

1 reference

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides

31 March 2020

1 reference

T2Rs function as bitter taste receptors

31 March 2020

1 reference

The human taste receptor hTAS2R14 responds to a variety of different bitter compounds

31 March 2020

1 reference

Bitter taste receptors for saccharin and acesulfame K.

31 March 2020

1 reference

Identification of coding single-nucleotide polymorphisms in human taste receptor genes involving bitter tasting

31 March 2020

1 reference

Identification of ligands for two human bitter T2R receptors

31 March 2020

1 reference

The repertoire of trace amine G-protein-coupled receptors: large expansion in zebrafish

31 March 2020

1 reference

A glance at G-protein-coupled receptors for lipid mediators: a growing receptor family with remarkably diverse ligands

31 March 2020

1 reference

Only six kingdoms of life

31 March 2020

1 reference

Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium

31 March 2020

1 reference

Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling

31 March 2020

1 reference

GPR1 encodes a putative G protein-coupled receptor that associates with the Gpa2p Galpha subunit and functions in a Ras-independent pathway

31 March 2020

1 reference

The Dictyostelium repertoire of seven transmembrane domain receptors

31 March 2020

1 reference

Manifestations of multicellularity: Dictyostelium reports in.

31 March 2020

1 reference

From plants to man: the GPCR "tree of life".

31 March 2020

1 reference

The evolutionarily triumphant G-protein-coupled receptor

31 March 2020

1 reference

RAMPs: The past, present and future.

31 March 2020

1 reference

Arrestins: ubiquitous regulators of cellular signaling pathways

31 March 2020

1 reference

G-protein signaling: back to the future

31 March 2020

1 reference

Rho GTPase-dependent transformation by G protein-coupled receptors

31 March 2020

1 reference

Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes

31 March 2020

1 reference

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

31 March 2020

1 reference

The arrangement of the transmembrane helices in the secretin receptor family of G-protein-coupled receptors.

31 March 2020

1 reference

Highly conserved aspartate 68, tryptophane 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP.

31 March 2020

1 reference

Multiple extracellular loop domains contribute critical determinants for agonist binding and activation of the secretin receptor

31 March 2020

1 reference

Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies

31 March 2020

1 reference

Role of charged amino acids conserved in the vasoactive intestinal polypeptide/secretin family of receptors on the secretin receptor functionality

31 March 2020

1 reference

Direct mapping of an agonist-binding domain within the parathyroid hormone/parathyroid hormone-related protein receptor by photoaffinity crosslinking

31 March 2020

1 reference

The role of the fourth extracellular domain of the rat corticotropin-releasing factor receptor type 1 in ligand binding

31 March 2020

1 reference

Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop

31 March 2020

1 reference

Three distinct epitopes on the extracellular face of the glucagon receptor determine specificity for the glucagon amino terminus

31 March 2020

1 reference

The human VPAC1 receptor: three-dimensional model and mutagenesis of the N-terminal domain

31 March 2020

1 reference

Lysine 195 and aspartate 196 in the first extracellular loop of the VPAC1 receptor are essential for high affinity binding of agonists but not of antagonists

31 March 2020

1 reference

CDD: a Conserved Domain Database for protein classification

31 March 2020

1 reference

Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97

31 March 2020

1 reference

Three adjacent serines in the extracellular domains of the CaR are required for L-amino acid-mediated potentiation of receptor function

31 March 2020

1 reference

Mapping the agonist-binding site of GABAB type 1 subunit sheds light on the activation process of GABAB receptors

31 March 2020

1 reference

Cloning, distribution and functional expression of the human mGlu6 metabotropic glutamate receptor

31 March 2020

1 reference

Mutations of the calcium-sensing receptor (CASR) in familial hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia

31 March 2020

1 reference

Efficacy of short-term monotherapy with maraviroc, a new CCR5 antagonist, in patients infected with HIV-1.

31 March 2020

1 reference

Proteinase-mediated cell signalling: targeting proteinase-activated receptors (PARs) by kallikreins and more

31 March 2020

1 reference

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7 January 2021

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Identifiers

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

281371

1047432273

0 references

281371

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=18382464

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017