Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A (Q24310210)

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Paola Massimi

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Stephen M Dilworth

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Lawrence Banks

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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language of work or name

English

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publication date

24 November 2005

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published in

Oncogene

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volume

24

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issue

53

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page(s)

7830-8

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cites work

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https://api.crossref.org/works/10.1038/SJ.ONC.1208935

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

20 April 2017

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Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

20 April 2017

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A new technique for the assay of infectivity of human adenovirus 5 DNA

20 April 2017

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Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

20 April 2017

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Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change

20 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1208935

Protein phosphatase 2A is the main phosphatase involved in the regulation of protein kinase B in rat adipocytes

20 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1208935

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

20 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1208935

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

20 April 2017

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https://api.crossref.org/works/10.1038/SJ.ONC.1208935

Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors

20 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Degradation of p53 only is not sufficient for the growth stimulatory effect of human papillomavirus 16 E6 oncoprotein in human embryonic fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.

21 January 2018

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Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Ganglioside loss promotes survival primarily by activating integrin-linked kinase/Akt without phosphoinositide 3-OH kinase signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

Phosphatidylinositol 3-Kinase Is a Key Regulator of Early Phase Differentiation in Keratinocytes

21 January 2018

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Enhancement of EGF- and PMA-mediated MAP kinase activation in cells expressing the human papillomavirus type 16 E5 protein

21 January 2018

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7 January 2021

Epidermal Ras blockade demonstrates spatially localized Ras promotion of proliferation and inhibition of differentiation

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7 January 2021

Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen.

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7 January 2021

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

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Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

7 January 2021

Keratinocyte apoptosis on type I collagen gel caused by lack of laminin 5/10/11 deposition and Akt signaling

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

7 January 2021

Protein kinase B/Akt is activated by polyomavirus middle-T antigen via a phosphatidylinositol 3-kinase-dependent mechanism

1 reference

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7 January 2021

Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

7 January 2021

The third subunit of protein phosphatase 2A (PP2A), a 55-kilodalton protein which is apparently substituted for by T antigens in complexes with the 36- and 63-kilodalton PP2A subunits, bears little resemblance to T antigens

1 reference

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7 January 2021

Alternatively spliced HPV-18 E6* protein inhibits E6 mediated degradation of p53 and suppresses transformed cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

7 January 2021

Activated Notch1 signaling cooperates with papillomavirus oncogenes in transformation and generates resistance to apoptosis on matrix withdrawal through PKB/Akt

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7 January 2021

Modulation of cellular apoptotic potential: contributions to oncogenesis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208935

7 January 2021

Association of human papillomavirus types 16 and 18 E6 proteins with p53.

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208935

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Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1398047

1046942463

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1398047

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference