SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin (Q24310658)

GOA release 2020-03-11

author

Or Gozani

14

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author name string

Eriko Michishita

1

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Ronald A McCord

2

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Elisabeth Berber

3

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Mitomu Kioi

4

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Hesed Padilla-Nash

5

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Mara Damian

6

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Peggie Cheung

7

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Rika Kusumoto

8

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Tiara L A Kawahara

9

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J Carl Barrett

10

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Howard Y Chang

11

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Vilhelm A Bohr

12

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Thomas Ried

13

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Katrin F Chua

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

15

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language of work or name

English

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publication date

27 March 2008

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published in

Nature

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volume

452

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issue

7186

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page(s)

492-6

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

19 March 2017

1 reference

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POT1 as a terminal transducer of TRF1 telomere length control

19 March 2017

1 reference

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

19 March 2017

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

19 March 2017

1 reference

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The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

19 March 2017

1 reference

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The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2

19 March 2017

1 reference

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TRF2 Protects Human Telomeres from End-to-End Fusions

19 March 2017

1 reference

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Genomic instability and aging-like phenotype in the absence of mammalian SIRT6

19 March 2017

1 reference

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Essential role of limiting telomeres in the pathogenesis of Werner syndrome

19 March 2017

1 reference

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

19 March 2017

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A DNA damage checkpoint response in telomere-initiated senescence

7 April 2017

1 reference

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DNA damage foci at dysfunctional telomeres

7 April 2017

1 reference

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Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.

7 April 2017

1 reference

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Replication and protection of telomeres

27 September 2017

1 reference

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The epigenetic regulation of mammalian telomeres

27 September 2017

1 reference

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WRN at telomeres: implications for aging and cancer

27 September 2017

1 reference

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Telomere dysfunction as a cause of genomic instability in Werner syndrome

27 September 2017

1 reference

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Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres

27 September 2017

1 reference

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MDC1 accelerates nonhomologous end-joining of dysfunctional telomeres

27 September 2017

2 references

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27 September 2017

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Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase

29 November 2018

1 reference

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Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Defective telomere lagging strand synthesis in cells lacking WRN helicase activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome arms

27 September 2017

1 reference

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Cellular senescence: mitotic clock or culture shock?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Multicolor Spectral Karyotyping of Human Chromosomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Unusual chromatin in human telomeres

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2646112

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18337721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prolongation of S phase and whole cell cycle in Werner's syndrome fibroblasts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18337721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Increased chromosome instability and accumulation of DNA double-strand breaks in Werner syndrome cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18337721

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE06736

1 reference

Dimensions Publication ID

747132

1044670645

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Fatcat ID

release_3maja2jlejgv3myfftvgh6c5vi

0 references

747132

1 reference

1 reference

1 reference