Leukemia-associated retinoic acid receptor alpha fusion partners, PML and PLZF, heterodimerize and colocalize to nuclear bodies (Q24311314)

negative regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

1 reference

13

S Waxman

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author name string

M H Koken

1

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A Reid

2

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F Quignon

3

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M K Chelbi-Alix

4

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J M Davies

5

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J H Kabarowski

6

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J Zhu

7

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S Dong

8

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S Chen

9

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Z Chen

10

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C C Tan

11

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J Licht

12

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H de Thé

14

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A Zelent

Proceedings of the National Academy of Sciences of the United States of America

15

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language of work or name

English

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publication date

16 September 1997

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published in

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volume

94

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issue

19

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page(s)

10255-60

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cites work

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Leukemia translocation gene, PLZF, is expressed with a speckled nuclear pattern in early hematopoietic progenitors

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Fusion between a novel Krüppel-like zinc finger gene and the retinoic acid receptor-alpha locus due to a variant t(11;17) translocation associated with acute promyelocytic leukaemia

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PML, a growth suppressor disrupted in acute promyelocytic leukemia

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Structure, localization and transcriptional properties of two classes of retinoic acid receptor alpha fusion proteins in acute promyelocytic leukemia (APL): structural similarities with a new family of oncoproteins

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Accelerated degradation of PML-retinoic acid receptor alpha (PML-RARA) oncoprotein by all-trans-retinoic acid in acute promyelocytic leukemia: possible role of the proteasome pathway

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PIC 1, a novel ubiquitin-like protein which interacts with the PML component of a multiprotein complex that is disrupted in acute promyelocytic leukaemia

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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Arsenic-induced PML targeting onto nuclear bodies: implications for the treatment of acute promyelocytic leukemia

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

19 March 2017

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Retinoic acid regulates aberrant nuclear localization of PML-RAR alpha in acute promyelocytic leukemia cells

19 March 2017

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A novel macromolecular structure is a target of the promyelocyte-retinoic acid receptor oncoprotein

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The PML/RAR alpha oncoprotein is a direct molecular target of retinoic acid in acute promyelocytic leukemia cells

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PML protein expression in hematopoietic and acute promyelocytic leukemia cells

27 September 2017

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PMLRAR homodimers: distinct DNA binding properties and heteromeric interactions with RXR

27 September 2017

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Rearrangements involving chromosome band 11Q23 in acute leukaemia

27 September 2017

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The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion

27 September 2017

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Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain

27 September 2017

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27 September 2017

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PML suppresses oncogenic transformation of NIH/3T3 cells by activated neu.

27 September 2017

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rpt-1, an intracellular protein from helper/inducer T cells that regulates gene expression of interleukin 2 receptor and human immunodeficiency virus type 1

27 September 2017

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Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus

27 September 2017

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Characterization of a Zinc Finger Gene Disrupted by the t(15;17) in Acute Promyelocytic Leukemia

27 September 2017

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PML-containing nuclear bodies: their spatial distribution in relation to other nuclear components

27 September 2017

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cAMP signalling is decisive for recovery of nuclear bodies (PODs) during maturation of RA-resistant t(15;17) promyelocytic leukemia NB4 cells expressing PML-RAR alpha

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=23349

Effect of PML and PML-RAR on the transactivation properties and subcellular distribution of steroid hormone receptors

27 September 2017

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Effect of retinoic acid isomers on proliferation, differentiation and PML relocalization in the APL cell line NB4.

27 September 2017

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The PML gene encodes a phosphoprotein associated with the nuclear matrix

27 September 2017

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A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

30 May 2018

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The RAR alpha-PLZF chimera associated with Acute Promyelocytic Leukemia has retained a sequence-specific DNA-binding domain.

30 May 2018

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Chromosomal translocations in human cancer.

21 January 2018

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Induction of the PML protein by interferons in normal and APL cells.

21 January 2018

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Reduced and altered DNA-binding and transcriptional properties of the PLZF-retinoic acid receptor-alpha chimera generated in t(11;17)-associated acute promyelocytic leukemia.

29 November 2018

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Transcriptional induction of the PML growth suppressor gene by interferons is mediated through an ISRE and a GAS element.

29 November 2018

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The BTB/POZ domain: a new protein-protein interaction motif common to DNA- and actin-binding proteins.

29 November 2018

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The acute promyelocytic leukaemia-associated PML gene is induced by interferon.

29 November 2018

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All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells

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12 December 2020

Structure and origin of the acute promyelocytic leukemia myl/RAR alpha cDNA and characterization of its retinoid-binding and transactivation properties

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12 December 2020

Acute promyelocytic leukemia

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The PML growth-suppressor has an altered expression in human oncogenesis

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12 December 2020