Insulin-induced activation of NADPH-dependent H2O2 generation in human adipocyte plasma membranes is mediated by Galphai2 (Q24311765)

positive regulation of respiratory burst

GOA release 2020-03-11

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Journal of Biological Chemistry

GOA release 2020-03-11

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H I Krieger-Brauer

1

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P K Medda

series ordinal

2

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H Kather

series ordinal

3

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language of work or name

English

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publication date

11 April 1997

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published in

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volume

272

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page(s)

10135-43

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issue

15

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Human fat cells possess a plasma membrane-bound H2O2-generating system that is activated by insulin via a mechanism bypassing the receptor kinase

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The stimulus-sensitive H2O2-generating system present in human fat-cell plasma membranes is multireceptor-linked and under antagonistic control by hormones and cytokines

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Antagonistic effects of different members of the fibroblast and platelet-derived growth factor families on adipose conversion and NADPH-dependent H2O2 generation in 3T3 L1-cells

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Pertussis toxin catalyzed ADP-ribosylation of a 41 kDa G-protein impairs insulin-stimulated glucose metabolism in BC3H-1 myocytes

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Human fat cell lipolysis is primarily regulated by inhibitory modulators acting through distinct mechanisms

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Insulin activates GTP binding to a 40 kDa protein in fat cells

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Insulin receptor function is inhibited by guanosine 5'-[gamma-thio]triphosphate (GTP[S])

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An insulin receptor peptide (1135-1156) stimulates guanosine 5'-[gamma-thio]triphosphate binding to the 67 kDa G-protein associated with the insulin receptor

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Photoaffinity labelling of cardiac membrane GTP-binding proteins in response to insulin

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Stimulation of high-affinity GTPase activity and cholera toxin-catalysed [32P]ADP-ribosylation of Gi by lysophosphatidic acid (LPA) in wild-type and alpha 2C10 adrenoceptor-transfected Rat 1 fibroblasts

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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Mn2(+)-binding properties of a recombinant protein-tyrosine kinase derived from the human insulin receptor

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Dual Mg2+ control of formyl-peptide-receptor--G-protein interaction in HL 60 cells. Evidence that the low-agonist-affinity receptor interacts with and activates the G-protein

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Activation of Adenylate Cyclase by Choleragen

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Opioid peptides promote cholera-toxin-catalysed ADP-ribosylation of the inhibitory guanine-nucleotide-binding protein (Gi) in membranes of neuroblastoma x glioma hybrid cells

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The biochemical basis of the NADPH oxidase of phagocytes.

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Insulin action impaired by deficiency of the G-protein subunit G ialpha2

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The action of islet activating protein (pertussis toxin) on insulin's ability to inhibit adenylate cyclase and activate cyclic AMP phosphodiesterases in hepatocytes

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A role for inositol-glycan mediators and G-proteins in insulin action

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Insulin inhibits the phosphorylation of alpha-Gi-2 in intact hepatocytes

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Stimulation of a glycosyl-phosphatidylinositol-specific phospholipase by insulin and the sulfonylurea, glimepiride, in rat adipocytes depends on increased glucose transport.

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Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes

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Insulin stimulates GDP release from G proteins in the rat and human liver plasma membranes

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7 January 2021

Guanine nucleotide binding regulatory proteins in liver from obese humans with and without type II diabetes: evidence for altered "cross-talk" between the insulin receptor and Gi-proteins

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Islet‐activating protein discriminates the antilipolytic mechanism of insulin from that of other antilipolytic compounds

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GTP-binding protein-activator sequences in the insulin receptor

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Guanosine 5'-(gamma-thio) triphosphate (GTP gamma S) inhibits phosphorylation of insulin receptor and a novel GTP-binding protein, Gir, from human placenta

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7 January 2021

G beta gamma subunits mediate mitogen-activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor

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In vivo coupling of insulin-like growth factor II/mannose 6-phosphate receptor to heteromeric G proteins. Distinct roles of cytoplasmic domains and signal sequestration by the receptor

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Activation of exocytosis by the heterotrimeric G protein Gi3

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Action of insulin modulated by pertussis toxin in rat adipocytes.

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