COMMD1 regulates the delta epithelial sodium channel (δENaC) through trafficking and ubiquitination (Q24311990)

negative regulation of protein localization to cell surface

GOA release 2020-03-11

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Biochemical and Biophysical Research Communications

GOA release 2020-03-11

protein ubiquitination

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4

Fiona J McDonald

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author name string

Tina Chang

series ordinal

1

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Ying Ke

series ordinal

2

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Kevin Ly

series ordinal

3

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language of work or name

English

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publication date

5 August 2011

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published in

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volume

411

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page(s)

506-11

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issue

3

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cites work

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Regulation of the epithelial sodium channel (ENaC) by membrane trafficking

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Solution structure of the COMMD1 N-terminal domain

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The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis

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The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes

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Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

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A novel role for XIAP in copper homeostasis through regulation of MURR1

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COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase

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Epithelial sodium channel (ENaC) is multi-ubiquitinated at the cell surface

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Roles of COMM-domain-containing 1 in stability and recruitment of the copper-transporting ATPase in a mouse hepatoma cell line

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Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.

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Molecular cloning and functional expression of a novel amiloride-sensitive Na+ channel

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The copper toxicosis gene product Murr1 directly interacts with the Wilson disease protein

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Identification of Murr1 as a regulator of the human delta epithelial sodium channel

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Protons activate the delta-subunit of the epithelial Na+ channel in humans

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Degenerin sites mediate proton activation of deltabetagamma-epithelial sodium channel

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COMMD proteins, a novel family of structural and functional homologs of MURR1

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Nedd4-2 catalyzes ubiquitination and degradation of cell surface ENaC.

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COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate

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Cell-specific expression of epithelial sodium channel alpha, beta, and gamma subunits in aldosterone-responsive epithelia from the rat: localization by in situ hybridization and immunocytochemistry

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Acute ENaC stimulation by cAMP in a kidney cell line is mediated by exocytic insertion from a recycling channel pool

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Identification of a new copper metabolism gene by positional cloning in a purebred dog population

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Mouse U2af1-rs1 is a neomorphic imprinted gene

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Regulation of endogenous ENaC functional expression by CFTR and ΔF508-CFTR in airway epithelial cells.

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COMMD1 downregulates the epithelial sodium channel through Nedd4-2

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Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

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Role of ubiquitylation in cellular membrane transport

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Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface

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COMMD1-mediated ubiquitination regulates CFTR trafficking.

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