A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor (Q24313393)

protein homodimerization activity

1 reference

Axin 1

1 reference

Wingless-type MMTV integration site family, member 3A

1 reference

Molecular and Cellular Biology

Guizhong Liu

1

Guizhong

Liu

1 reference

20 October 2023

Anna Bafico

series ordinal

2

author given names

Anna

author last names

Bafico

1 reference

20 October 2023

Violaine K Harris

series ordinal

3

author given names

Violaine K

author last names

Harris

1 reference

20 October 2023

Stuart A Aaronson

series ordinal

4

author given names

Stuart A

author last names

Aaronson

1 reference

20 October 2023

language of work or name

English

0 references

publication date

August 2003

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published in

0 references

volume

23

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issue

16

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page(s)

5825-35

0 references

cites work

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Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

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A member of the Frizzled protein family mediating axis induction by Wnt-5A

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Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt coreceptor

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Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains

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Wnt signaling and cancer

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Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family

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Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling

19 March 2017

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arrow encodes an LDL-receptor-related protein essential for Wingless signalling

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A frizzled homolog functions in a vertebrate Wnt signaling pathway

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27 September 2017

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Regulation of signal transduction and signal diversity by receptor oligomerization

27 September 2017

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A soluble form of Wnt-1 protein with mitogenic activity on mammary epithelial cells

27 September 2017

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The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix

27 September 2017

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Secreted int-1 protein is associated with the cell surface

27 September 2017

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27 September 2017

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Pathway specificity by the bifunctional receptor frizzled is determined by affinity for wingless

27 September 2017

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Switching signals on or off by receptor dimerization

30 May 2018

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Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

30 May 2018

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Boca, an endoplasmic reticulum protein required for wingless signaling and trafficking of LDL receptor family members in Drosophila.

30 May 2018

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Ligand receptor interactions in the Wnt signaling pathway in Drosophila

29 November 2018

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Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms

29 November 2018

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Developmental biology. Making head or tail of Dickkopf.

29 November 2018

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Signaling specificity by Frizzled receptors in Drosophila.

29 November 2018

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