siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy (Q24314616)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

title

siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

Unc-51 like autophagy activating kinase 1

1 January 2020

main subject

autophagy

0 references

1 reference

GOA release 2020-03-11

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3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

author name string

Edmond Y W Chan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

Serkan Kir

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

language of work or name

English

0 references

publication date

26 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

1 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

volume

282

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1 January 2020

issue

35

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1 January 2020

page(s)

25464-25474

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

1 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Role of mitochondrial permeability transition pores in mitochondrial autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

The role of autophagy during the early neonatal starvation period

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Autophagy genes are essential for dauer development and life-span extension in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Dictyostelium macroautophagy mutants vary in the severity of their developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Growth factor regulation of autophagy and cell survival in the absence of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Ceramide-mediated macroautophagy involves inhibition of protein kinase B and up-regulation of beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Inhibition of macroautophagy triggers apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Escape of intracellular Shigella from autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Isolation of autophagocytosis mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

A Unified Nomenclature for Yeast Autophagy-Related Genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Formation of the approximately 350-kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

A ubiquitin-like system mediates protein lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Microtubules facilitate autophagosome formation and fusion of autophagosomes with endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

LC3, an autophagosome marker, can be incorporated into protein aggregates independent of autophagy: caution in the interpretation of LC3 localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Tor-mediated induction of autophagy via an Apg1 protein kinase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

An evolutionary proteomics approach identifies substrates of the cAMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Role and regulation of starvation-induced autophagy in the Drosophila fat body

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Direct induction of autophagy by Atg1 inhibits cell growth and induces apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Human ULK1, a novel serine/threonine kinase related to UNC-51 kinase of Caenorhabditis elegans: cDNA cloning, expression, and chromosomal assignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Mouse ULK2, a novel member of the UNC-51-like protein kinases: unique features of functional domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Unc-51-like kinase 1/2-mediated endocytic processes regulate filopodia extension and branching of sensory axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

A mouse serine/threonine kinase homologous to C. elegans UNC51 functions in parallel fiber formation of cerebellar granule neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Guanine nucleotide exchange on heterotrimeric Gi3 protein controls autophagic sequestration in HT-29 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Erk1/2-dependent phosphorylation of Galpha-interacting protein stimulates its GTPase accelerating activity and autophagy in human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Off-target effects associated with long dsRNAs in Drosophila RNAi screens

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Autophagic degradation of N-linked glycoproteins is downregulated in differentiated human colon adenocarcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Role of Unc51.1 and its binding partners in CNS axon outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Identification of mouse ULK1, a novel protein kinase structurally related to C. elegans UNC-51

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Function of the Dictyostelium discoideum Atg1 kinase during autophagy and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

inferred from DOI database lookup

7 January 2021

based on heuristic

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M703663200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M703663200

2 references

Consolidated OpenCitations Corpus – April 2017

1647186

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17595159%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

1647186

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

1647186