Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors (Q24315640)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15009664%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors (English)

1 reference

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Serine and arginine rich splicing factor 4

25 December 2019

main subject

dementia

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1 reference

Serine and arginine rich splicing factor 9

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CUGBP Elav-like family member 4

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CUGBP Elav-like family member 3

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Transformer 2 beta homolog

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U2 small nuclear RNA auxiliary factor 2

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Serine and arginine rich splicing factor 7

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Polypyrimidine tract binding protein 1

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Serine and arginine rich splicing factor 6

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positive regulation of mRNA splicing, via spliceosome

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frontotemporal dementia

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4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15009664%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

Junning Wang

1

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25 December 2019

Qing-Sheng Gao

2

1 reference

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25 December 2019

Yingzi Wang

3

1 reference

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25 December 2019

Stefan Stamm

5

1 reference

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25 December 2019

Athena Andreadis

6

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25 December 2019

language of work or name

English

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publication date

1 March 2004

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Journal of Neurochemistry

25 December 2019

published in

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25 December 2019

volume

88

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25 December 2019

issue

5

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25 December 2019

page(s)

1078-1090

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Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia

25 December 2019

cites work

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tau Exon 10 expression involves a bipartite intron 10 regulatory sequence and weak 5' and 3' splice sites

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hnRNP-G promotes exon 7 inclusion of survival motor neuron (SMN) via direct interaction with Htra2-beta1

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SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1

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7 January 2021

HnRNP G and Tra2beta: opposite effects on splicing matched by antagonism in RNA binding

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cis-elements involved in alternative splicing in the rat beta-tropomyosin gene: the 3'-splice site of the skeletal muscle exon 7 is the major site of blockage in nonmuscle cells

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hnRNP A1 recruited to an exon in vivo can function as an exon splicing silencer

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7 January 2021

Amount of RNA secondary structure required to induce an alternative splice

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7 January 2021

Tau consists of a set of proteins with repeated C-terminal microtubule-binding domains and variable N-terminal domains

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Frontotemporal dementia: its rediscovery

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Tau is enriched on dynamic microtubules in the distal region of growing axons

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Tau binds to the distal axon early in development of polarity in a microtubule- and microfilament-dependent manner

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7 January 2021