Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression (Q24316570)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

Nuclear receptor subfamily 5 group A member 1

11 November 2019

main subject

1 reference

primary sex determination

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1

Mark W Nachtigal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

6

Holly A Ingraham

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author name string

Yoshifumi Hirokawa

2

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Debra L Enyeart-VanHouten

3

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John N Flanagan

4

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Gary D Hammer

5

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language of work or name

English

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publication date

1 May 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

volume

93

1 reference

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11 November 2019

issue

3

1 reference

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11 November 2019

page(s)

445-454

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Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer

11 November 2019

cites work

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7 January 2021

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

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Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

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Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

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Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

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Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

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Ahch, the mouse homologue of DAX1: cloning, characterization and synteny with GyK, the glycerol kinase locus.

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7 January 2021

The POU-specific domain of Pit-1 is essential for sequence-specific, high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions

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7 January 2021

The nuclear receptor steroidogenic factor 1 acts at multiple levels of the reproductive axis

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7 January 2021

DAX-1 inhibits SF-1-mediated transactivation via a carboxy-terminal domain that is deleted in adrenal hypoplasia congenita

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7 January 2021

Expression of a candidate sex-determining gene during mouse testis differentiation.

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WT-1 is required for early kidney development

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Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols

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A transcriptional silencing domain in DAX-1 whose mutation causes adrenal hypoplasia congenita

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Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

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Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

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A clinical overview of WT1 gene mutations

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A cell-specific nuclear receptor is essential for adrenal and gonadal development and sexual differentiation.

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The nuclear receptor superfamily: the second decade

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Antagonism of WT1 activity by protein self-association.

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Mutations in the DAX-1 gene give rise to both X-linked adrenal hypoplasia congenita and hypogonadotropic hypogonadism

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7 January 2021

Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product

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Steroidogenic Factor 1: A Key Determinant of Endocrine Development and Function

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Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome

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7 January 2021

Expression of the Wilms' tumor gene WT1 in the murine urogenital system

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7 January 2021

Nuclear receptors in Sicily: all in the famiglia.

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The candidate Wilms' tumour gene is involved in genitourinary development

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7 January 2021

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

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7 January 2021

Mice deficient in the orphan receptor steroidogenic factor 1 lack adrenal glands and gonads but express P450 side-chain-cleavage enzyme in the placenta and have normal embryonic serum levels of corticosteroids

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7 January 2021

Nuclear receptor steroidogenic factor 1 regulates the müllerian inhibiting substance gene: a link to the sex determination cascade

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7 January 2021

Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice.

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7 January 2021

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

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7 January 2021

Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function.

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7 January 2021

Dax1 antagonizes Sry action in mammalian sex determination

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7 January 2021

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

1 reference

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7 January 2021

An unusual member of the nuclear hormone receptor superfamily responsible for X-linked adrenal hypoplasia congenita

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7 January 2021

DNA binding and transcriptional repression by DAX-1 blocks steroidogenesis

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7 January 2021

10.1016/S0092-8674(00)81172-1

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

3598957

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9590178%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

3598957

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

3598957