Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses (Q24317227)

positive regulation of excitatory postsynaptic potential

1 reference

Brain-specific angiogenesis inhibitor 1-associated protein 2

1 reference

Glutamate receptor, ionotropic, NMDA2B (epsilon 2)

1 reference

Glutamate receptor, ionotropic, AMPA1 (alpha 1)

1 reference

Glutamate receptor, metabotropic 4

1 reference

SH3 and multiple ankyrin repeat domains 2

1 reference

Abl interactor 1

1 reference

Glutamate receptor, metabotropic 1

1 reference

SH3 and multiple ankyrin repeat domains 1

1 reference

Homer scaffolding protein 1

1 reference

Glutamate receptor, ionotropic, NMDA1 (zeta 1)

1 reference

Glutamate receptor, metabotropic 5

1 reference

SH3 and multiple ankyrin repeat domains 3

1 reference

Chiara Verpelli

1

0 references

Bruno Di Stefano

Bruno Di Stefano

7

0 references

Vania Broccoli

Vania Broccoli

9

0 references

Carlo Sala

Carlo Sala

12

0 references

Alexander Dityatev

Alexander Dityatev

11

0 references

Renato Mantegazza

Renato Mantegazza

8

0 references

Michela Chiappalone

5

Michela Chiappalone

0 references

author name string

Elena Dvoretskova

2

0 references

Cinzia Vicidomini

3

0 references

Francesca Rossi

4

0 references

Michael Schoen

6

0 references

Tobias M Böckers

Journal of Biological Chemistry

10

0 references

language of work or name

English

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publication date

7 October 2011

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published in

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volume

286

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issue

40

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page(s)

34839-50

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describes a project that uses

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3186429/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

19 March 2017

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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

19 March 2017

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Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

19 March 2017

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Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease

19 March 2017

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The postsynaptic density proteins Homer and Shank form a polymeric network structure

19 March 2017

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A pilot open label, single dose trial of fenobam in adults with fragile X syndrome.

19 March 2017

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19 March 2017

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Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

19 March 2017

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Contribution of SHANK3 mutations to autism spectrum disorder

19 March 2017

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Abelson interacting protein 1 (Abi-1) is essential for dendrite morphogenesis and synapse formation

19 March 2017

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

19 March 2017

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Identification of a recurrent breakpoint within the SHANK3 gene in the 22q13.3 deletion syndrome

19 March 2017

1 reference

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A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses

19 March 2017

1 reference

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Molecular characterisation of the 22q13 deletion syndrome supports the role of haploinsufficiency of SHANK3/PROSAP2 in the major neurological symptoms

19 March 2017

1 reference

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Altered synaptic plasticity in a mouse model of fragile X mental retardation

19 March 2017

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Disruption of the ProSAP2 gene in a t(12;22)(q24.1;q13.3) is associated with the 22q13.3 deletion syndrome

19 March 2017

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Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

19 March 2017

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Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis

19 March 2017

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Elongation factor 2 and fragile X mental retardation protein control the dynamic translation of Arc/Arg3.1 essential for mGluR-LTD

19 March 2017

1 reference

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Interstitial 22q13 deletions: genes other than SHANK3 have major effects on cognitive and language development

19 March 2017

1 reference

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Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1.

19 March 2017

1 reference

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An architectural framework that may lie at the core of the postsynaptic density

19 March 2017

1 reference

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Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Inhibition of dendritic spine morphogenesis and synaptic transmission by activity-inducible protein Homer1a

19 March 2017

1 reference

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ProSAP/Shank postsynaptic density proteins interact with insulin receptor tyrosine kinase substrate IRSp53

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

ProSAP/Shank proteins - a family of higher order organizing molecules of the postsynaptic density with an emerging role in human neurological disease

19 March 2017

1 reference

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The Shank family of scaffold proteins

19 March 2017

1 reference

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Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP family

19 March 2017

1 reference

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Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

19 March 2017

1 reference

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Conserved role of intragenic DNA methylation in regulating alternative promoters

19 March 2017

1 reference

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Regulation of dendritic spine morphology and synaptic function by Shank and Homer

7 April 2017

1 reference

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SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.

10 May 2017

1 reference

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Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation

27 September 2017

1 reference

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Long-term depression in the CNS.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Metabotropic glutamate receptor subtype 5 antagonism in learning and memory

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Synaptic cross-talk between N-methyl-D-aspartate receptors and LAPSER1-beta-catenin at excitatory synapses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Interaction of Cupidin/Homer2 with two actin cytoskeletal regulators, Cdc42 small GTPase and Drebrin, in dendritic spines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Regulation of dendritic spine morphology by SPIN90, a novel Shank binding partner.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Proteomic analysis of activity-dependent synaptic plasticity in hippocampal neurons.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Long-term depression: multiple forms and implications for brain function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral models

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Seven in absentia homolog 1A mediates ubiquitination and degradation of group 1 metabotropic glutamate receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Distinct presenilin‐dependent and presenilin‐independent γ‐secretases are responsible for total cellular Aβ production

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

A novel algorithm for precise identification of spikes in extracellularly recorded neuronal signals.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Activity-induced Polo-like kinase 2 is required for homeostatic plasticity of hippocampal neurons during epileptiform activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186429

Shank expression is sufficient to induce functional dendritic spine synapses in aspiny neurons.

30 May 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Chromosome 22q13.3 deletion syndrome with a de novo interstitial 22q13.3 cryptic deletion disrupting SHANK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Novel de novo SHANK3 mutation in autistic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

DNA methylation regulates tissue-specific expression of Shank3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Tyrosine phosphatases regulate AMPA receptor trafficking during metabotropic glutamate receptor-mediated long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Replica-moulded polydimethylsiloxane culture vessel lids attenuate osmotic drift in long-term cell cultures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Low-frequency stimulation enhances burst activity in cortical cultures during development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

A self-adapting approach for the detection of bursts and network bursts in neuronal cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Extracellular signal-regulated protein kinase activation is required for metabotropic glutamate receptor-dependent long-term depression in hippocampal area CA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

C-terminal synaptic targeting elements for postsynaptic density proteins ProSAP1/Shank2 and ProSAP2/Shank3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Differential roles for group 1 mGluR subtypes in induction and expression of chemically induced hippocampal long-term depression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Experience-dependent modification of mechanisms of long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Synaptic Strength as a Function of Post- versus Presynaptic Expression of the Neural Cell Adhesion Molecule NCAM

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.258384

Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1.

21 January 2018

1 reference