PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo (Q24317781)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21803845%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

PMLRARα binds to Fas and suppresses Fas-mediated apoptosis through recruiting c-FLIP in vivo (English)

1 reference

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9 February 2020

0 references

0 references

Fas cell surface death receptor

1 reference

Caspase 8

1 reference

Fas associated via death domain

1 reference

CASP8 and FADD like apoptosis regulator

1 reference

PML nuclear body scaffold

1 reference

Promyelocytic leukemia

1 reference

Fas (TNF receptor superfamily member 6)

1 reference

author

Zuzana Berkova

2

1 reference

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9 February 2020

Urszula Daniluk

5

1 reference

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9 February 2020

author name string

Rong-Hua Tao

1

1 reference

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9 February 2020

Jillian F Wise

3

1 reference

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9 February 2020

Abdol-Hossein Rezaeian

4

1 reference

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9 February 2020

Xue Ao

6

1 reference

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9 February 2020

David H Hawke

7

1 reference

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9 February 2020

Judith E Karp

8

1 reference

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9 February 2020

Hui-Kuan Lin

9

1 reference

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9 February 2020

Jeffrey J Molldrem

10

1 reference

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9 February 2020

Felipe Samaniego

11

1 reference

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9 February 2020

language of work or name

English

0 references

publication date

29 July 2011

1 reference

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9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21803845%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

118

1 reference

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9 February 2020

issue

11

1 reference

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9 February 2020

page(s)

3107-3118

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UBE1L is a retinoid target that triggers PML/RARalpha degradation and apoptosis in acute promyelocytic leukemia

9 February 2020

cites work

1 reference

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Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

19 March 2017

1 reference

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PML regulates apoptosis at endoplasmic reticulum by modulating calcium release

19 March 2017

1 reference

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Cytoplasmic PML function in TGF-beta signalling

19 March 2017

1 reference

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Role of PML and the PML-nuclear body in the control of programmed cell death

19 March 2017

1 reference

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PML protein isoforms and the RBCC/TRIM motif

19 March 2017

1 reference

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The function of PML in p53-dependent apoptosis

19 March 2017

1 reference

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The transcriptional role of PML and the nuclear body

19 March 2017

1 reference

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

19 March 2017

1 reference

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PML is essential for multiple apoptotic pathways

19 March 2017

1 reference

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Covalent modification of PML by the sentrin family of ubiquitin-like proteins

19 March 2017

1 reference

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The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

19 March 2017

1 reference

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Structure, dynamics and functions of promyelocytic leukaemia nuclear bodies

19 March 2017

1 reference

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Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemia

7 April 2017

1 reference

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Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

27 September 2017

1 reference

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Milatuzumab - a promising new immunotherapeutic agent.

27 September 2017

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Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency

27 September 2017

1 reference

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The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers

27 September 2017

1 reference

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Mechanism of Fas signaling regulation by human herpesvirus 8 K1 oncoprotein

27 September 2017

1 reference

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c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells

27 September 2017

1 reference

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All EGF(ErbB) receptors have preformed homo- and heterodimeric structures in living cells.

27 September 2017

1 reference

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Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein

27 September 2017

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UBE1L represses PML/RAR{alpha} by targeting the PML domain for ISG15ylation

27 September 2017

1 reference

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K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosis

27 September 2017

1 reference

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cFLIP regulation of lymphocyte activation and development

27 September 2017

1 reference

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Testicular zinc finger protein recruits histone deacetylase 2 and suppresses the transactivation function and intranuclear foci formation of agonist-bound androgen receptor competitively with TIF2.

27 September 2017

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A sumoylation site in PML/RARA is essential for leukemic transformation.

27 September 2017

1 reference

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PML nuclear bodies: dynamic sensors of DNA damage and cellular stress

27 September 2017

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PML nuclear bodies and apoptosis

27 September 2017

1 reference

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Loss of the tumor suppressor PML in human cancers of multiple histologic origins

27 September 2017

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Acute promyelocytic leukaemia:a review

27 September 2017

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Arsenic trioxide induces apoptosis in leukemia/lymphoma cell lines via the CD95/CD95L system.

27 September 2017

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Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein

27 September 2017

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The PML/RARalpha fusion protein inhibits tumor necrosis factor-alpha-induced apoptosis in U937 cells and acute promyelocytic leukemia blasts

27 September 2017

1 reference

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Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

27 September 2017

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Transgenic expression of PML/RARalpha impairs myelopoiesis

27 September 2017

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The acute promyelocytic leukemia-specific PML-RAR alpha fusion protein inhibits differentiation and promotes survival of myeloid precursor cells

27 September 2017

1 reference

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Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation.

30 May 2018

1 reference

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Pro-proliferative function of the long isoform of PML-RARalpha involved in acute promyelocytic leukemia

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3291494

Arsenic trioxide overcomes apoptosis inhibition in K562/ADM cells by regulating vital components in apoptotic pathway

29 November 2018

1 reference

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Mutations of the PML tumor suppressor gene in acute promyelocytic leukemia

29 November 2018

1 reference

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CD95 engagement induces disseminated endothelial cell apoptosis in vivo: immunopathologic implications.

29 November 2018

1 reference

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A mechanism of cell survival: sequestration of Fas by the HGF receptor Met.

29 November 2018

1 reference

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Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

29 November 2018

1 reference

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Fas (CD95, APO-1) antigen expression and function in murine liver endothelial cells: implications for the regulation of apoptosis in liver endothelial cells.

29 November 2018

1 reference

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Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

29 November 2018

1 reference

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Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.

29 November 2018

1 reference

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The role of p53 and the CD95 (APO-1/Fas) death system in chemotherapy-induced apoptosis

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21803845

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2011-04-349670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21803845%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21803845%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference