Nitrite reductase activity and inhibition of H₂S biogenesis by human cystathionine ß-synthase (Q24319814)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904041

positive regulation of cystathionine beta-synthase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904043

negative regulation of cystathionine beta-synthase activity

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904042

5-methyltetrahydrofolate-homocysteine methyltransferase reductase

GOA release 2020-03-11

1 reference

Cystathionine beta-synthase

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Pramod K Yadav

2

0 references

author name string

Carmen Gherasim

1

0 references

Omer Kabil

3

0 references

Wei-Ning Niu

4

0 references

Ruma Banerjee

Creative Commons Attribution 4.0 International

5

0 references

language of work or name

English

0 references

publication date

2014

0 references

published in

PLOS One

0 references

volume

9

0 references

issue

1

0 references

page(s)

e85544

0 references

copyright license

start time

8 January 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Human cystathionine beta-synthase is a heme sensor protein. Evidence that the redox sensor is heme and not the vicinal cysteines in the CXXC motif seen in the crystal structure of the truncated enzyme

19 March 2017

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H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase

19 March 2017

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3-Mercaptopyruvate sulfurtransferase produces hydrogen sulfide and bound sulfane sulfur in the brain

19 March 2017

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Quantitative Systems Pharmacology Model of NO Metabolome and Methemoglobin Following Long-Term Infusion of Sodium Nitrite in Humans

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Kinetics of reversible reductive carbonylation of heme in human cystathionine β-synthase.

27 September 2017

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Enzymology of H2S biogenesis, decay and signaling

27 September 2017

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Characterization of the mechanism and magnitude of cytoglobin-mediated nitrite reduction and nitric oxide generation under anaerobic conditions

27 September 2017

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Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols

27 September 2017

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Integrating nitric oxide, nitrite and hydrogen sulfide signaling in the physiological adaptations to hypoxia: A comparative approach

27 September 2017

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High turnover rates for hydrogen sulfide allow for rapid regulation of its tissue concentrations

27 September 2017

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Nitric oxide: A pleiotropic signal in the nervous system

27 September 2017

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Reversible heme-dependent regulation of human cystathionine β-synthase by a flavoprotein oxidoreductase.

27 September 2017

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PLP-dependent H(2)S biogenesis

27 September 2017

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Human neuroglobin functions as a redox-regulated nitrite reductase

27 September 2017

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The quantitative significance of the transsulfuration enzymes for H2S production in murine tissues

27 September 2017

1 reference

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Characterization of erythrocytic uptake and release and disposition pathways of nitrite, nitrate, methemoglobin, and iron-nitrosyl hemoglobin in the human circulation

27 September 2017

1 reference

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27 September 2017

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Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology

27 September 2017

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Hydrogen sulfide: from brain to gut.

27 September 2017

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H2S biogenesis by human cystathionine gamma-lyase leads to the novel sulfur metabolites lanthionine and homolanthionine and is responsive to the grade of hyperhomocysteinemia

27 September 2017

1 reference

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Modulation of the heme electronic structure and cystathionine beta-synthase activity by second coordination sphere ligands: The role of heme ligand switching in redox regulation.

27 September 2017

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Impeded electron transfer from a pathogenic FMN domain mutant of methionine synthase reductase and its responsiveness to flavin supplementation

27 September 2017

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27 September 2017

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27 September 2017

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Hydrogen sulphide and its therapeutic potential

27 September 2017

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Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase

27 September 2017

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Free radical biology and medicine: it's a gas, man!

27 September 2017

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27 September 2017

1 reference

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Reaction mechanism and regulation of cystathionine beta-synthase

27 September 2017

1 reference

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27 September 2017

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Active cystathionine beta-synthase can be expressed in heme-free systems in the presence of metal-substituted porphyrins or a chemical chaperone

27 September 2017

1 reference

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27 September 2017

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Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme

30 May 2018

1 reference

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Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0085544

Mercuric chloride-induced spin or ligation state changes in ferric or ferrous human cystathionine beta-synthase inhibit enzyme activity

21 January 2018

1 reference

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Reactions of ferrous neuroglobin and cytoglobin with nitrite under anaerobic conditions.

21 January 2018

1 reference

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Effects of heme ligand mutations including a pathogenic variant, H65R, on the properties of human cystathionine beta-synthase

21 January 2018

1 reference

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A functional transsulfuration pathway in the brain links to glutathione homeostasis

21 January 2018

1 reference

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21 January 2018

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Plant and cyanobacterial hemoglobins reduce nitrite to nitric oxide under anoxic conditions

21 January 2018

1 reference

12 December 2020

Cooperativity in the dissociation of nitric oxide from hemoglobin

1 reference

12 December 2020

Enzyme-independent formation of nitric oxide in biological tissues

1 reference

12 December 2020

Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration

1 reference

12 December 2020

Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites

1 reference

12 December 2020

Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation

1 reference

12 December 2020

Evidence for heme-mediated redox regulation of human cystathionine beta-synthase activity

1 reference

12 December 2020

Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites

1 reference

12 December 2020

Nitrite reductase activity of hemoglobin S (sickle) provides insight into contributions of heme redox potential versus ligand affinity

1 reference

12 December 2020