Translational homeostasis via the mRNA cap-binding protein, eIF4E (Q24320659)

Eukaryotic translation initiation factor 4E binding protein 1

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Kelch like family member 25

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Eukaryotic translation initiation factor 4E

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author

Nahum Sonenberg

10

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Yvan Martineau

object named as

Yvan Martineau

8

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Akiko Yanagiya

object named as

Akiko Yanagiya

1

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author name string

Eigo Suyama

2

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Hironori Adachi

3

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Yuri V Svitkin

4

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Pedro Aza-Blanc

5

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Hiroaki Imataka

6

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Satoshi Mikami

7

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Ze'ev A Ronai

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

9

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language of work or name

English

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publication date

29 June 2012

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published in

Molecular Cell

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volume

46

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issue

6

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page(s)

847-58

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Poly(A) binding protein (PABP) homeostasis is mediated by the stability of its inhibitor, Paip2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Ribosome loading onto the mRNA cap is driven by conformational coupling between eIF4G and eIF4E

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Hierarchical phosphorylation of the translation inhibitor 4E-BP1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Production of high-titer helper-free retroviruses by transient transfection

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Regulation of translation initiation by FRAP/mTOR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Targeting the eukaryotic translation initiation factor 4E for cancer therapy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

A hypoxia-controlled cap-dependent to cap-independent translation switch in breast cancer.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

On the art of identifying effective and specific siRNAs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing CUL-3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Alternatively spliced transcripts from the Drosophila eIF4E gene produce two different Cap-binding proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

Targeting of protein ubiquitination by BTB–Cullin 3–Roc1 ubiquitin ligases

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4085128

4E binding protein 1 expression is inversely correlated to the progression of gastrointestinal cancers

29 November 2018

1 reference

12 December 2020

eIF4E Association with 4E-BP Decreases Rapidly Following Fertilization in Sea Urchin

1 reference

12 December 2020

BTB/POZ domain proteins are putative substrate adaptors for cullin 3 ubiquitin ligases

1 reference

12 December 2020

Immunological detection of the messenger RNA cap-binding protein

1 reference

12 December 2020

Regulated phosphorylation and low abundance of HeLa cell initiation factor eIF-4F suggest a role in translational control. Heat shock effects on eIF-4F

1 reference

12 December 2020

Expression of mTOR signaling pathway markers in prostate cancer progression

1 reference

12 December 2020

10.1016/J.MOLCEL.2012.04.004

Identifiers

DOI

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652290

652290

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1 reference

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