A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage (Q24321669)

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A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage

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English	A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage	scientific article	A Supramodular FHA/BRCT-Repeat Architecture Mediates Nbs1 Adaptor Function in Response to DNA Damage

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9 February 2020

A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage (English)

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9 February 2020

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9 February 2020

Stephen P Jackson

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9 February 2020

Stephen J Smerdon

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Janette Lloyd

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9 February 2020

Julie A Clapperton

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9 February 2020

Lesley F Haire

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9 February 2020

Edgar Hartsuiker

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9 February 2020

Jiejin Li

6

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1 October 2009

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9 February 2020

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9 February 2020

139

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9 February 2020

1

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9 February 2020

100-111

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9 February 2020

Recruitment of Saccharomyces cerevisiae Dnl4-Lif1 complex to a double-strand break requires interactions with Yku80 and the Xrs2 FHA domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Forkhead-associated domain of yeast Xrs2, a homolog of human Nbs1, promotes nonhomologous end joining through interaction with a ligase IV partner protein, Lif1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Human CtIP promotes DNA end resection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

1 reference

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19 March 2017

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Crystal structure of an Xrcc4-DNA ligase IV complex

1 reference

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19 March 2017

Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization

1 reference

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19 March 2017

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

19 March 2017

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

7 April 2017

Reading protein modifications with interaction domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

7 April 2017

Structure and function of the phosphothreonine-specific FHA domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Early events in the mammalian response to DNA double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Molecular characterization of the role of the Schizosaccharomyces pombe nip1+/ctp1+ gene in DNA double-strand break repair in association with the Mre11-Rad50-Nbs1 complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

1 reference

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27 September 2017

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

The NBS1-ATM connection revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900601

27 September 2017

Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms

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27 September 2017

ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1.

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27 September 2017

Protein N-terminal methionine excision.

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27 September 2017

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

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27 September 2017

An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele

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27 September 2017

Mutations in the Nijmegen breakage syndrome gene in medulloblastomas

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30 May 2018

Positional cloning of the gene for Nijmegen breakage syndrome

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30 May 2018

Extent of N-terminal modifications in cytosolic proteins from eukaryotes.

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29 November 2018

Detection of a tandem BRCT in Nbs1 and Xrs2 with functional implications in the DNA damage response

1 reference

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29 November 2018

Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode

1 reference

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29 November 2018

Structure of the BRCT repeat domain of MDC1 and its specificity for the free COOH-terminal end of the gamma-H2AX histone tail

1 reference

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29 November 2018

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

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29 November 2018

A rapid and simple procedure for high-efficiency lithium acetate transformation of cryopreserved Schizosaccharomyces pombe cells

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7 January 2021

based on heuristic

inferred from DOI database lookup

Nbs1 Flexibly Tethers Ctp1 and Mre11-Rad50 to Coordinate DNA Double-Strand Break Processing and Repair

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2009.07.043

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene tagging and gene replacement using recombinase-mediated cassette exchange in Schizosaccharomyces pombe

1 reference

https://api.crossref.org/works/10.1016%2FJ.CELL.2009.07.043

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1016/J.CELL.2009.07.043

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19804756%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

release_s3ku5oywxnfebilmaqiebdjnbi

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https://api.fatcat.wiki/v0/release/s3ku5oywxnfebilmaqiebdjnbi

24 November 2022

based on heuristic

mapped directly with Wikidata item

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9 February 2020

1 reference

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9 February 2020

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