The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo (Q24322122)

positive regulation of ERK1 and ERK2 cascade

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Michael J Rogers

8

0 references

Ken Mackie

object named as

Ken Mackie

5

0 references

author name string

Lauren S Whyte

1

0 references

Erik Ryberg

2

0 references

Natalie A Sims

3

0 references

Susan A Ridge

4

0 references

Peter J Greasley

6

0 references

Ruth A Ross

Proceedings of the National Academy of Sciences of the United States of America

7

0 references

language of work or name

English

0 references

publication date

22 September 2009

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published in

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volume

106

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page(s)

16511-6

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issue

38

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cites work

The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation

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GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

19 March 2017

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Novel cannabinoid receptors

19 March 2017

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The orphan receptor GPR55 is a novel cannabinoid receptor

19 March 2017

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The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

19 March 2017

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The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

19 March 2017

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Peripheral cannabinoid receptor, CB2, regulates bone mass

19 March 2017

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The enigmatic pharmacology of GPR55

19 March 2017

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The putative cannabinoid receptor GPR55 plays a role in mechanical hyperalgesia associated with inflammatory and neuropathic pain

19 March 2017

1 reference

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Identification of GPR55 as a lysophosphatidylinositol receptor

19 March 2017

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In silico patent searching reveals a new cannabinoid receptor

19 March 2017

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Interleukin-11 receptor signaling is required for normal bone remodeling

19 March 2017

1 reference

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Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption

19 March 2017

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Integrin clustering enables anandamide-induced Ca2+ signaling in endothelial cells via GPR55 by protection against CB1-receptor-triggered repression

27 September 2017

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Actin cytoskeletal organisation in osteoclasts: a model to decipher transmigration and matrix degradation

27 September 2017

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GPR55: a new member of the cannabinoid receptor clan?

27 September 2017

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Versatility of GPCR recognition by drugs: from biological implications to therapeutic relevance

27 September 2017

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GPCR functional selectivity has therapeutic impact

27 September 2017

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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors

27 September 2017

1 reference

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Evidence for novel cannabinoid receptors

27 September 2017

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The endocannabinoid system and its therapeutic exploitation

27 September 2017

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The role of prenylated small GTP-binding proteins in the regulation of osteoclast function

27 September 2017

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Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions.

27 September 2017

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The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

27 September 2017

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Signalling pathways involved in the mitogenic action of lysophosphatidylinositol

27 September 2017

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Novel pro-survival functions of the Kruppel-like transcription factor Egr2 in promotion of macrophage colony-stimulating factor-mediated osteoclast survival downstream of the MEK/ERK pathway.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737440

Single-dose kinetics of deuterium-labelled cannabidiol in man after smoking and intravenous administration

30 May 2018

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Assay of plasma cannabidiol by capillary gas chromatography/ion trap mass spectroscopy following high-dose repeated daily oral administration in humans

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737440

Kinetics of the osteoclast cytoskeleton during the resorption cycle in vitro.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737440

Reciprocal role of ERK and NF-kappaB pathways in survival and activation of osteoclasts

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-beta in bone remodeling in females but not in males

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

Cardiotrophin-1 Is an Osteoclast-Derived Stimulus of Bone Formation Required for Normal Bone Remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

Involvement of neuronal cannabinoid receptor CB1 in regulation of bone mass and bone remodeling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0902743106

Perinatal testosterone surge is required for normal adult bone size but not for normal bone remodeling.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737440

The small GTP-binding protein, rho p21, is involved in bone resorption by regulating cytoskeletal organization in osteoclasts.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737440

Role of osteoclast extracellular signal-regulated kinase (ERK) in cell survival and maintenance of cell polarity

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rho-A is critical for osteoclast podosome organization, motility, and bone resorption

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Osteoclast formation in the mouse coculture assay

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19805329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0902743106

1 reference

4757662

ADS bibcode

2009PNAS..10616511W

0 references

4757662

1 reference

1 reference

1 reference