BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent manner (Q24324399)

Activating transcription factor 5

GOA release 2020-03-11

1 reference

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Douglas Dluzen

1

0 references

Guangfu Li

2

0 references

Diana Tacelosky

3

0 references

Matthew Moreau

4

0 references

David X Liu

Journal of Biological Chemistry

5

0 references

language of work or name

English

0 references

publication date

4 March 2011

0 references

published in

0 references

volume

286

0 references

issue

9

0 references

page(s)

7705-13

0 references

cites work

Regulation of the human CHOP gene promoter by the stress response transcription factor ATF5 via the AARE1 site in human hepatoma HepG2 cells

1 reference

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ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Regulated expression of ATF5 is required for the progression of neural progenitor cells to neurons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Inhibition of apoptosis by ATFx: a novel role for a member of the ATF/CREB family of mammalian bZIP transcription factors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Bcl-2 protein expression during murine development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Induction of a Common Pathway of Apoptosis by Staurosporine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

27 September 2017

The BCL-2 family reunion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Inactivation of p53 function in cultured human mammary epithelial cells turns the telomere-length dependent senescence barrier from agonescence into crisis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

ATF5 promotes cell survival through transcriptional activation of Hsp27 in H9c2 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

The retinoblastoma protein binds the promoter of the survival gene bcl-2 and regulates its transcription in epithelial cells through transcription factor AP-2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

NF-kappaB activates Bcl-2 expression in t(14;18) lymphoma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Pi 1 binding sites are negative regulators of bcl-2 expression in pre-B cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

Identification of a p53-dependent negative response element in the bcl-2 gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3045024

ATF5 regulates the proliferation and differentiation of oligodendrocytes.

27 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207639

Re-expression of transcription factor ATF5 in hepatocellular carcinoma induces G2-M arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207639

Regulation of neuronal survival and death by E2F-dependent gene repression and derepression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207639

Staurosporine induces apoptosis through both caspase-dependent and caspase-independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.207639

Regulation of Bcl-2 expression by C/EBP in t(14;18) lymphoma cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212266

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activating transcription factor 2 controls Bcl-2 promoter activity in growth plate chondrocytes.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212266