The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins (Q24328753)

GOA release 2020-03-11

kinase activity

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GOA release 2020-03-11

author name string

S B McMahon

1

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H A Van Buskirk

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K A Dugan

3

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T D Copeland

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M D Cole

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma

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language of work or name

English

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publication date

7 August 1998

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published in

Cell

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volume

94

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issue

3

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page(s)

363-74

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cites work

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7 January 2021

Oncogenic activity of the c-Myc protein requires dimerization with Max.

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Mad-Max transcriptional repression is mediated by ternary complex formation with mammalian homologs of yeast repressor Sin3

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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The ornithine decarboxylase gene is a transcriptional target of c-Myc

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Gene-based sequence-tagged-sites (STSs) as the basis for a human gene map

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An essential domain of the c-myc protein interacts with a nuclear factor that is also required for E1A-mediated transformation

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7 January 2021

The myc oncogene: its role in transformation and differentiation

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

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Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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DNA-binding and trans-activation properties of Drosophila E2F and DP proteins

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Cellular responses to DNA damage: cell-cycle checkpoints, apoptosis and the roles of p53 and ATM

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Induction of apoptosis in fibroblasts by c-myc protein

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Reciprocal regulation of adipogenesis by Myc and C/EBP alpha

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Myc and Max homologs in Drosophila

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Association of adenovirus early-region 1A proteins with cellular polypeptides

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DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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7 January 2021

TATA-binding protein and the retinoblastoma gene product bind to overlapping epitopes on c-Myc and adenovirus E1A protein

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A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

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A Short Polypeptide Marker Sequence Useful for Recombinant Protein Identification and Purification

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When is a lipid kinase not a lipid kinase? When it is a protein kinase

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An amino-terminal c-myc domain required for neoplastic transformation activates transcription

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Ataxia-telangiectasia: a multifaceted genetic disorder associated with defective signal transduction

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c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II

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7 January 2021

Dominant negative mutants of Myc inhibit cooperation of both Myc and adenovirus serotype-5 E1a with Ras

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7 January 2021

Fragments of ATM which have dominant-negative or complementing activity

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Role of the Rb/E2F pathway in cell growth control

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Functional properties of a Drosophila homolog of the E2F1 gene

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Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping

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B-myc inhibits neoplastic transformation and transcriptional activation by c-myc

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BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

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An amino-terminal domain of Mxi1 mediates anti-Myc oncogenic activity and interacts with a homolog of the yeast transcriptional repressor SIN3

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Drosophila Myc is oncogenic in mammalian cells and plays a role in the diminutive phenotype

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Disruption of RB/E2F-1 interaction by single point mutations in E2F-1 enhances S-phase entry and apoptosis

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A repeating amino acid motif in CDC23 defines a family of proteins and a new relationship among genes required for mitosis and RNA synthesis

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Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators

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Definition of regions in human c-myc that are involved in transformation and nuclear localization

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How do protein kinases discriminate between serine/threonine and tyrosine? Structural insights from the insulin receptor protein-tyrosine kinase.

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Signalling through the lipid products of phosphoinositide-3-OH kinase

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The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

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TOR kinase domains are required for two distinct functions, only one of which is inhibited by rapamycin

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A time-efficient, linear-space local similarity algorithm

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10.1016/S0092-8674(00)81479-8

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

2798182

2798182

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference