Overexpression of alpha2A-adrenergic receptors contributes to type 2 diabetes (Q24336126)

negative regulation of insulin secretion involved in cellular response to glucose stimulus

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

11

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Valeriya Lyssenko

14

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Patrik Rorsman

12

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Jonatan Tuncel

Jonatan Tuncel

9

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Thomas M Reinbothe

Thomas M Reinbothe

8

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Ola Hansson

Ola Hansson

5

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Lena Eliasson

Lena Eliasson

10

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Albert Salehi

Albert Salehi

13

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Anders H Rosengren

1

Anders H Rosengren

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author name string

Ramunas Jokubka

2

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Damon Tojjar

3

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Charlotte Granhall

4

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Dai-Qing Li

6

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Vini Nagaraj

7

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Holger Luthman

15

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Erik Renström

A genome-wide association study identifies novel risk loci for type 2 diabetes

16

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language of work or name

English

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publication date

8 January 2010

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published in

Science

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volume

327

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page(s)

217-20

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issue

5962

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cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1176827

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1176827

Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1176827

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Linkage of type 2 diabetes mellitus and of age at onset to a genetic location on chromosome 10q in Mexican Americans

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Novel aspects of the molecular mechanisms controlling insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Regulation of releasable vesicle pool sizes by protein kinase A-dependent phosphorylation of SNAP-25.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

A genetic polymorphism of the alpha2-adrenergic receptor increases autonomic responses to stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Complex haplotypes derived from noncoding polymorphisms of the intronless alpha2A-adrenergic gene diversify receptor expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Physiological significance of alpha(2)-adrenergic receptor subtype diversity: one receptor is not enough

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

Transgenic mice overexpressing alpha2A-adrenoceptors in pancreatic beta-cells show altered regulation of glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Neurotransmitter-induced inhibition of exocytosis in insulin-secreting beta cells by activation of calcineurin.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Activation by adrenaline of a low-conductance G protein-dependent K+ channel in mouse pancreatic B cells

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Protein kinase A-dependent and -independent stimulation of exocytosis by cAMP in mouse pancreatic B-cells

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Separately inherited defects in insulin exocytosis and beta-cell glucose metabolism contribute to type 2 diabetes

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Pathophysiological and genetic characterization of the major diabetes locus in GK rats

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Phenotyping of individual pancreatic islets locates genetic defects in stimulus secretion coupling to Niddm1i within the major diabetes locus in GK rats

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1176827

7 January 2021

Identifiers

DOI

10.1126/SCIENCE.1176827

1 reference

Consolidated OpenCitations Corpus – April 2017

1905213

1905213

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference