The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death (Q24336280)

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27 December 2019

title

The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death (English)

1 reference

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Connector enhancer of kinase suppressor of Ras 1

27 December 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

3

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27 December 2019

author name string

Shahrooz Rabizadeh

1

1 reference

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27 December 2019

Ramnik J Xavier

2

1 reference

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27 December 2019

Juliocesar Bernabeortiz

4

1 reference

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27 December 2019

Marco Lopez-Ilasaca

5

1 reference

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27 December 2019

Andrei Khokhlatchev

6

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27 December 2019

Pamela Mollahan

7

1 reference

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27 December 2019

Gerd P Pfeifer

8

1 reference

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27 December 2019

Joseph Avruch

9

1 reference

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27 December 2019

Brian Seed

10

1 reference

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27 December 2019

language of work or name

English

0 references

publication date

9 April 2004

1 reference

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Journal of Biological Chemistry

27 December 2019

published in

1 reference

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27 December 2019

volume

279

1 reference

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27 December 2019

issue

28

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27 December 2019

page(s)

29247-29254

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CNK, a RAF-binding multidomain protein required for RAS signaling

27 December 2019

cites work

1 reference

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Critical contribution of linker proteins to Raf kinase activation

21 January 2018

1 reference

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Bimodal regulation of RAF by CNK in Drosophila

21 January 2018

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Functional analysis of CNK in RAS signaling

21 January 2018

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The dark side of Ras: regulation of apoptosis

21 January 2018

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Ras signalling and apoptosis

21 January 2018

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Identification of a novel Ras-regulated proapoptotic pathway

21 January 2018

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Identification of Nore1 as a potential Ras effector

21 January 2018

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Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.

21 January 2018

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RASSF3 and NORE1: identification and cloning of two human homologues of the putative tumor suppressor gene RASSF1

21 January 2018

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The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacy

21 January 2018

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The putative tumor suppressor RASSF1A homodimerizes and heterodimerizes with the Ras-GTP binding protein Nore1

21 January 2018

1 reference

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Methylation of the RASSF1A gene in human cancers

21 January 2018

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Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers

21 January 2018

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The t(1;3) breakpoint-spanning genes LSAMP and NORE1 are involved in clear cell renal cell carcinomas

21 January 2018

1 reference

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Nore1 inhibits tumor cell growth independent of Ras or the MST1/2 kinases

21 January 2018

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Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression

21 January 2018

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The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis

21 January 2018

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The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation

21 January 2018

1 reference

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The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

21 January 2018

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The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

21 January 2018

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Neurotrophin dependence mediated by p75NTR: contrast between rescue by BDNF and NGF.

21 January 2018

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Mutant K-ras enhances apoptosis in embryonic stem cells in combination with DNA damage and is associated with increased levels of p19(ARF).

21 January 2018

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Identification of protein complexes required for efficient sister chromatid cohesion

21 January 2018

1 reference

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Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf

21 January 2018

1 reference

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Ras-effector interactions: after one decade

21 January 2018

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Understanding Ras: 'it ain't over 'til it's over'.

21 January 2018

1 reference

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Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

21 January 2018

1 reference

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KSR is a scaffold required for activation of the ERK/MAPK module

21 January 2018

1 reference

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MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

21 January 2018

1 reference

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A mammalian scaffold complex that selectively mediates MAP kinase activation

21 January 2018

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The organization of INAD-signaling complexes by a multivalent PDZ domain protein in Drosophila photoreceptor cells ensures sensitivity and speed of signaling

21 January 2018

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The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

1 reference

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

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The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

21 January 2018

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Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

21 January 2018

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

21 January 2018

1 reference

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Frizzled receptors activate a novel JNK-dependent pathway that may lead to apoptosis

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401699200

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1074/JBC.M401699200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15075335%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference