3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase (Q24336639)

activation of protein kinase B activity

GOA release 2020-03-11

1 reference

Phosphoinositide-dependent kinase 1 Dmel_CG1210

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

11

A Ashworth

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author name string

D R Alessi

1

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M Deak

2

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A Casamayor

3

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F B Caudwell

4

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N Morrice

5

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D G Norman

6

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P Gaffney

7

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C B Reese

8

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C N MacDougall

9

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D Harbison

10

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M Bownes

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

12

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language of work or name

English

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publication date

1 October 1997

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published in

Current Biology

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volume

7

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page(s)

776-89

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issue

10

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cites work

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Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

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Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt.

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

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PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

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PDK1, one of the missing links in insulin signal transduction?

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Signaling pathway involved in the activation of heart 6-phosphofructo-2-kinase by insulin

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Phosphorylation and Activation of Heart 6-Phosphofructo-2-kinase by Protein Kinase B and Other Protein Kinases of the Insulin Signaling Cascades

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Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

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Mechanism of activation of protein kinase B by insulin and IGF-1

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3

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The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

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PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface

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The pleckstrin homology domain: an intriguing multifunctional protein module

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Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

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Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

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Developmental regulation of expression and activity of multiple forms of the Drosophila RAC protein kinase

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The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth.

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Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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The muscle pattern of a segment of Drosophila may be determined by neurons and not by contributing myoblasts

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How do germ cells choose their sex? Drosophila as a paradigm

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The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

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Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

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Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Flexible protein sequence patterns

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10.1016/S0960-9822(06)00336-8

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

release_eowrqea5t5fu7d6pwjffz24tca

3159574

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eowrqea5t5fu7d6pwjffz24tca

24 November 2022

mapped directly with Wikidata item

3159574

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference