Inflammatory cytokines induce phosphorylation and ubiquitination of prostate suppressor protein NKX3.1 (Q24337092)

Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1

GOA release 2020-03-11

protein ubiquitination

1 reference

1 reference

Mark C Markowski

1

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Cai Bowen

series ordinal

2

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Edward P Gelmann

series ordinal

3

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language of work or name

English

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publication date

1 September 2008

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published in

Cancer Research

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volume

68

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issue

17

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page(s)

6896-901

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2586101

NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity

19 March 2017

1 reference

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Topors functions as an E3 ubiquitin ligase with specific E2 enzymes and ubiquitinates p53

19 March 2017

1 reference

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The topoisomerase I-binding RING protein, topors, is associated with promyelocytic leukemia nuclear bodies

19 March 2017

1 reference

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Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

19 March 2017

1 reference

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The smooth muscle gamma-actin gene promoter is a molecular target for the mouse bagpipe homologue, mNkx3-1, and serum response factor

19 March 2017

1 reference

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Roles for Nkx3.1 in prostate development and cancer

19 March 2017

1 reference

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Inflammation in prostate carcinogenesis

19 March 2017

1 reference

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NKX3.1 is regulated by protein kinase CK2 in prostate tumor cells

27 September 2017

1 reference

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Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer

27 September 2017

1 reference

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Human prostate cancer precursors and pathobiology.

27 September 2017

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Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.

27 September 2017

1 reference

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Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression

27 September 2017

1 reference

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DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1.

27 September 2017

1 reference

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Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5.

27 September 2017

1 reference

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Incidental lymphocytic prostatitis. Selective involvement with nonmalignant glands

27 September 2017

1 reference

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Decreased NKX3.1 protein expression in focal prostatic atrophy, prostatic intraepithelial neoplasia, and adenocarcinoma: association with gleason score and chromosome 8p deletion.

30 May 2018

1 reference

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Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation

29 November 2018

1 reference

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Interleukin-6 regulates prostate-specific protein expression in prostate carcinoma cells by activation of the androgen receptor

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757402

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tumor necrosis factor-alpha sensitizes prostate cancer cells to gamma-irradiation-induced apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757402

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The VIOXX in Prostate Cancer Prevention study: cardiovascular events observed in the rofecoxib 25 mg and placebo treatment groups

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18757402