A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair (Q24337655)

5'-flap endonuclease activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Agata Smogorzewska

1

0 references

Stephen Elledge

11

0 references

Takamune T. Saito

object named as

Takamune T Saito

3

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author name string

Rohini Desetty

2

0 references

Michael Schlabach

4

0 references

Francis P Lach

5

0 references

Mathew E Sowa

6

0 references

Alan B Clark

7

0 references

Thomas A Kunkel

8

0 references

J Wade Harper

9

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Monica P Colaiácovo

DNA polymerase POLN participates in cross-link repair and homologous recombination

10

0 references

language of work or name

English

0 references

publication date

9 July 2010

0 references

published in

Molecular Cell

0 references

volume

39

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issue

1

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page(s)

36-47

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cites work

1 reference

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Evidence for the involvement of human DNA polymerase N in the repair of DNA interstrand cross-links

19 March 2017

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Defining the human deubiquitinating enzyme interaction landscape

19 March 2017

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Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

19 March 2017

1 reference

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Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

19 March 2017

1 reference

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Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

19 March 2017

1 reference

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The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells

19 March 2017

1 reference

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

19 March 2017

1 reference

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Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

19 March 2017

1 reference

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PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

19 March 2017

1 reference

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UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

19 March 2017

1 reference

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Identification of novel restriction endonuclease-like fold families among hypothetical proteins

19 March 2017

1 reference

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High-efficiency bypass of DNA damage by human DNA polymerase Q

19 March 2017

1 reference

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

19 March 2017

1 reference

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The genetics of Caenorhabditis elegans

19 March 2017

1 reference

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The structure of the catalytic subunit FANCL of the Fanconi anemia core complex

19 March 2017

1 reference

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Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates

19 March 2017

1 reference

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

19 March 2017

1 reference

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Identification of Holliday junction resolvases from humans and yeast

19 March 2017

1 reference

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Xpf and not the Fanconi anaemia proteins or Rev3 accounts for the extreme resistance to cisplatin in Dictyostelium discoideum

19 March 2017

1 reference

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The DNA damage response: ten years after

19 March 2017

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hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes

19 March 2017

1 reference

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Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2

19 March 2017

1 reference

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Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks

19 March 2017

1 reference

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Identification of the breast cancer susceptibility gene BRCA2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Mechanism of replication-coupled DNA interstrand crosslink repair

27 September 2017

1 reference

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Structural and functional relationships of the XPF/MUS81 family of proteins

27 September 2017

1 reference

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Low-fidelity DNA synthesis by human DNA polymerase theta.

27 September 2017

1 reference

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Cancer proliferation gene discovery through functional genomics.

27 September 2017

1 reference

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Profiling of UV-induced ATM/ATR signaling pathways.

27 September 2017

1 reference

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Translesion synthesis: Y-family polymerases and the polymerase switch

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Vertebrate POLQ and POLbeta cooperate in base excision repair of oxidative DNA damage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance

27 September 2017

1 reference

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Synthetic junctions as tools to identify and characterize Holliday junction resolvases

27 September 2017

1 reference

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Checking on DNA damage in S phase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

The Fanconi anaemia gene FANCC promotes homologous recombination and error-prone DNA repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

ATR couples FANCD2 monoubiquitination to the DNA-damage response

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Initiating cellular stress responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

FANCL replaces BRCA1 as the likely ubiquitin ligase responsible for FANCD2 monoubiquitination.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Identification and characterization of the human mus81-eme1 endonuclease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Rev1 is essential for DNA damage tolerance and non-templated immunoglobulin gene mutation in a vertebrate cell line.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Susceptibility of Fanconi's anaemia fibroblasts to chromosome damage by carcinogens

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

The FANCM ortholog Fml1 promotes recombination at stalled replication forks and limits crossing over during DNA double-strand break repair

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Caenorhabditis elegans POLQ-1 and HEL-308 function in two distinct DNA interstrand cross-link repair pathways.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Modeling Werner Syndrome in Drosophila melanogaster: hyper-recombination in flies lacking WRN-like exonuclease

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Endonucleolytic function of MutLalpha in human mismatch repair

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Cancer in Fanconi anemia.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919743

Familial constitutional panmyelocytopathy, Fanconi's anemia (F.A.). I. Clinical aspects

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20603073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Fragility and spiralization anomalies of the chromosomes in three cases, including fraternal twins, with Fanconi's anemia, type Estren-Dameshek

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20603073

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2010.06.023

1 reference

release_a5ehc4wrnzfujjbmhmzgme3ice

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a5ehc4wrnzfujjbmhmzgme3ice

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

1 reference

PubMed publication ID

20603073

1 reference