The polycomb group protein EZH2 is required for mammalian circadian clock function (Q24337692)

regulation of circadian rhythm

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Period circadian clock 2

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Cryptochrome 1 (photolyase-like)

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Cryptochrome 2 (photolyase-like)

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Aryl hydrocarbon receptor nuclear translocator-like

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Period circadian clock 1

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Enhancer of zeste 2 polycomb repressive complex 2 subunit

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Circadian locomotor output cycles kaput

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Jason P DeBruyne

3

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David R Weaver

object named as

David R Weaver

5

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Thomas Jenuwein

6

object named as

Thomas Jenuwein

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author name string

Jean-Pierre Etchegaray

1

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Xiaoming Yang

2

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Antoine H F M Peters

4

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Steven M Reppert

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

28 July 2006

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published in

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volume

281

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issue

30

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page(s)

21209-15

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cites work

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Posttranslational mechanisms regulate the mammalian circadian clock

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Feedback repression is required for mammalian circadian clock function

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A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo

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Rhythmic CLOCK-BMAL1 binding to multiple E-box motifs drives circadian Dbp transcription and chromatin transitions

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The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

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A transcription factor response element for gene expression during circadian night

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A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

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The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

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Translating the Histone Code

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The key to development: interpreting the histone code?

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Light induces chromatin modification in cells of the mammalian circadian clock.

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Histone acetyltransferase-dependent chromatin remodeling and the vascular clock

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Circadian and light-induced transcription of clock gene Per1 depends on histone acetylation and deacetylation

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Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation

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The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation

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Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer

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The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3.

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Role of polycomb group proteins in stem cell self-renewal and cancer.

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Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

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The polycomb-group gene Ezh2 is required for early mouse development

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Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development

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Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity

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Methylation of histones: playing memory with DNA.

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Direct association between mouse PERIOD and CKIepsilon is critical for a functioning circadian clock

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Partitioning and plasticity of repressive histone methylation states in mammalian chromatin

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A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex

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A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock

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Bimodal regulation of mPeriod promoters by CREB-dependent signaling and CLOCK/BMAL1 activity

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A serum shock induces circadian gene expression in mammalian tissue culture cells

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Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3.

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Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

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Differential regulation of mammalian period genes and circadian rhythmicity by cryptochromes 1 and 2

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Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

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Molecular mechanisms of the biological clock in cultured fibroblasts

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Resetting central and peripheral circadian oscillators in transgenic rats

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Circadian gene expression in individual fibroblasts: cell-autonomous and self-sustained oscillators pass time to daughter cells

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Light-independent role of CRY1 and CRY2 in the mammalian circadian clock.

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PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator

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Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

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An epigenetic road map for histone lysine methylation

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Vernalization requires epigenetic silencing of FLC by histone methylation

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Rhythmic histone acetylation underlies transcription in the mammalian circadian clock

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Epigenetics and cancer

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inferred from DOI database lookup

7 January 2021

based on heuristic

The dissonance mutation at the no-on-transient-A locus of D. melanogaster: genetic control of courtship song and visual behaviors by a protein with putative RNA-binding motifs

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