TNF-alpha induced c-IAP1/TRAF2 complex translocation to a Ubc6-containing compartment and TRAF2 ubiquitination (Q24529129)

2

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Xiaoming Li

3

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Sai-Xia Ying

4

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John A Hanover

5

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Jonathan D Ashwell

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

6

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language of work or name

English

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publication date

18 May 2005

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published in

The EMBO Journal

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volume

24

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issue

10

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page(s)

1886-98

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cites work

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TNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2

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CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

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Physical interaction between specific E2 and Hect E3 enzymes determines functional cooperativity

24 March 2017

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Cloning of human ubiquitin-conjugating enzymes UbcH6 and UbcH7 (E2-F1) and characterization of their interaction with E6-AP and RSP5

24 March 2017

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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor

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Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast

24 March 2017

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Role of Cue1p in ubiquitination and degradation at the ER surface

24 March 2017

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A protein translocation defect linked to ubiquitin conjugation at the endoplasmic reticulum

24 March 2017

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

24 March 2017

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The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins

24 March 2017

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Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapy

24 March 2017

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The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators

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Endoplasmic reticulum (ER)-associated degradation of T cell receptor subunits. Involvement of ER-associated ubiquitin-conjugating enzymes (E2s)

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Themes and variations on ubiquitylation

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Ubiquitin-mediated proteolysis of a short-lived regulatory protein depends on its cellular localization

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Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

24 March 2017

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Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling

24 March 2017

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Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

24 March 2017

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TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

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c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

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Ubiquitination and translocation of TRAF2 is required for activation of JNK but not of p38 or NF-kappaB.

27 September 2017

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The fusion oncoprotein PML-RARalpha induces endoplasmic reticulum (ER)-associated degradation of N-CoR and ER stress.

27 September 2017

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Tumor necrosis factor (TNF)-induced germinal center kinase-related (GCKR) and stress-activated protein kinase (SAPK) activation depends upon the E2/E3 complex Ubc13-Uev1A/TNF receptor-associated factor 2 (TRAF2).

27 September 2017

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The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition

27 September 2017

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A role for mammalian Ubc6 homologues in ER-associated protein degradation.

27 September 2017

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Endoplasmic reticulum dysfunction--a common denominator for cell injury in acute and degenerative diseases of the brain?

27 September 2017

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IL-18-stimulated GADD45 beta required in cytokine-induced, but not TCR-induced, IFN-gamma production.

27 September 2017

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Translocation of TRAF proteins regulates apoptotic threshold of cells

27 September 2017

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ER protein quality control and proteasome-mediated protein degradation

27 September 2017

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Calreticulin: one protein, one gene, many functions.

27 September 2017

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TNF receptor associated factors in cytokine signaling.

27 September 2017

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Apoptosis: Silencing the death receptors

27 September 2017

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Cooperation of both TNF receptors in inducing apoptosis: involvement of the TNF receptor-associated factor binding domain of the TNF receptor 75.

27 September 2017

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Tumor necrosis factor: a pleiotropic cytokine and therapeutic target

27 September 2017

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Tumor necrosis factor receptor superfamily members and their ligands

27 September 2017

1 reference

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Identification of two lysosomal membrane glycoproteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

Both TNF receptors are required for TNF-mediated induction of apoptosis in PC60 cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

Induction of apoptosis in mature T cells by tumour necrosis factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

Endoplasmic reticulum stress causes thyroglobulin retention in this organelle and triggers activation of nuclear factor-kappa B via tumor necrosis factor receptor-associated factor 2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

Inhibitors of apoptosis proteins in prostate cancer cell lines

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1142588

A crucial role for p80 TNF-R2 in amplifying p60 TNF-R1 apoptosis signals in T lymphocytes

29 November 2018

1 reference

12 December 2020

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site

1 reference

12 December 2020

TNFR80-dependent enhancement of TNFR60-induced cell death is mediated by TNFR-associated factor 2 and is specific for TNFR60

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12 December 2020

Apoptotic crosstalk of TNF receptors: TNF-R2-induces depletion of TRAF2 and IAP proteins and accelerates TNF-R1-dependent activation of caspase-8

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12 December 2020

Cytotoxic effect of TNF and lymphotoxin on T lymphoblasts

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600649

1 reference

1 reference

1 reference

PubMed publication ID

15861135

1 reference