CYR61 (CCN1) is essential for placental development and vascular integrity (Q24540206)

GOA release 2020-03-11

Simon C Watkins

5

1 reference

ORCID Public Data File 2021

author name string

Fan-E Mo

1

0 references

Andrew G Muntean

2

0 references

Chih-Chiun Chen

3

0 references

Donna B Stolz

4

0 references

Lester F Lau

Molecular and Cellular Biology

6

0 references

language of work or name

English

0 references

publication date

December 2002

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published in

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volume

22

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issue

24

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page(s)

8709-20

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cites work

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CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

24 March 2017

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24 March 2017

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24 March 2017

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Promoter function and structure of the growth factor-inducible immediate early gene cyr61

24 March 2017

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Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

24 March 2017

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Identification of integrin alpha(M)beta(2) as an adhesion receptor on peripheral blood monocytes for Cyr61 (CCN1) and connective tissue growth factor (CCN2): immediate-early gene products expressed in atherosclerotic lesions

24 March 2017

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24 March 2017

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Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

24 March 2017

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Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

24 March 2017

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Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

24 March 2017

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Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

24 March 2017

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Structure, mapping, and expression of fisp-12, a growth factor-inducible gene encoding a secreted cysteine-rich protein

24 March 2017

1 reference

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The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans

24 March 2017

1 reference

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The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta

24 March 2017

1 reference

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Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

24 March 2017

1 reference

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Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice

24 March 2017

1 reference

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Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation

24 March 2017

1 reference

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Mechanisms of angiogenesis

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Placental development: lessons from mouse mutants

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Vascular-specific growth factors and blood vessel formation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands

27 September 2017

1 reference

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Angiogenesis-dependent diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

The angiogenic factor Cyr61 activates a genetic program for wound healing in human skin fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Promoter function of the angiogenic inducer Cyr61gene in transgenic mice: tissue specificity, inducibility during wound healing, and role of the serum response element

27 September 2017

1 reference

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Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

CYR61 stimulates human skin fibroblast migration through Integrin alpha vbeta 5 and enhances mitogenesis through integrin alpha vbeta 3, independent of its carboxyl-terminal domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Expression and function of CYR61, an angiogenic factor, in breast cancer cell lines and tumor biopsies.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Adhesion of human skin fibroblasts to Cyr61 is mediated through integrin alpha 6beta 1 and cell surface heparan sulfate proteoglycans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Placental failure in mice lacking the mammalian homolog of glial cells missing, GCMa

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia.

27 September 2017

1 reference

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The connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed (CCN) family

27 September 2017

1 reference

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The CCN family of angiogenic regulators: the integrin connection

27 September 2017

1 reference

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Vascular endothelial growth factor C induces angiogenesis in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Cyr61, a product of a growth factor-inducible immediate-early gene, promotes cell proliferation, migration, and adhesion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Implantation and the placenta: key pieces of the development puzzle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

The modular architecture of a new family of growth regulators related to connective tissue growth factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Cyr61, product of a growth factor-inducible immediate early gene, is associated with the extracellular matrix and the cell surface

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Expression of the growth factor-inducible immediate early gene cyr61 correlates with chondrogenesis during mouse embryonic development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Targeted mutations in cell adhesion genes: what have we learned from them?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Morphogenesis of the syncytium in the mouse placenta. Ultrastructural study.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=139880

10.1128/MCB.22.24.8709-8720.2002

29 November 2018

Identifiers

DOI

1 reference

716055

716055

1 reference

1 reference

1 reference