SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation (Q24548288)

2

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I Das

3

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J Li

4

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M Gurney

5

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A Pauley

6

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I Chui

7

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R J Deshaies

8

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J Kitajewski

Molecular and Cellular Biology

9

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language of work or name

English

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publication date

November 2001

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published in

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volume

21

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issue

21

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page(s)

7403-15

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cites work

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Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

24 March 2017

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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

24 March 2017

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Presenilin is required for activity and nuclear access of Notch in Drosophila

24 March 2017

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

24 March 2017

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A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

24 March 2017

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sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins

24 March 2017

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How proteolysis drives the cell cycle

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Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

24 March 2017

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Jagged: a mammalian ligand that activates Notch1

24 March 2017

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Notch4 and Jagged-1 induce microvessel differentiation of rat brain endothelial cells

24 March 2017

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Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

24 March 2017

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Nuclear access and action of notch in vivo

24 March 2017

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Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans

24 March 2017

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

24 March 2017

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SCF and Cullin/Ring H2-based ubiquitin ligases

24 March 2017

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beta-catenin is a target for the ubiquitin-proteasome pathway

7 April 2017

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Production of high-titer helper-free retroviruses by transient transfection

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7 April 2017

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7 April 2017

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7 April 2017

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The NOTCH4 locus is associated with susceptibility to schizophrenia

7 April 2017

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Q vectors, bicistronic retroviral vectors for gene transfer

27 September 2017

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Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription

27 September 2017

1 reference

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Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

27 September 2017

1 reference

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Notchless encodes a novel WD40-repeat-containing protein that modulates Notch signaling activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Interaction between Wingless and Notch signaling pathways mediated by dishevelled.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

The suppressor of hairless protein participates in notch receptor signaling

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=99913

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11585921

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11585921