New approaches to understanding p53 gene tumor mutation spectra (Q33818052)

29 July 2017

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title

New approaches to understanding p53 gene tumor mutation spectra (English)

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29 July 2017

Hollstein M

1

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29 July 2017

Hergenhahn M

2

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29 July 2017

Yang Q

3

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29 July 2017

Bartsch H

4

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29 July 2017

Wang ZQ

5

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29 July 2017

Hainaut P

6

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29 July 2017

language of work or name

English

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publication date

1 December 1999

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29 July 2017

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29 July 2017

431

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29 July 2017

2

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29 July 2017

199-209

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IARC Database of p53 gene mutations in human tumors and cell lines: updated compilation, revised formats and new visualisation tools

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Instability and decay of the primary structure of DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53, the cellular gatekeeper for growth and division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Regulation of p53 downstream genes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 modulation of TFIIH-associated nucleotide excision repair activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

A rapid PCR fidelity assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

On the origins of tumor mutations in cancer genes: insights from the p53 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Spectrum of point mutations in the coding region of the hypoxanthine-guanine phosphoribosyltransferase (hprt) gene in human T-lymphocytes in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Software for the analysis of mutations at the human hprt gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Sunburn and p53 in the onset of skin cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Hepatocellular carcinoma: from gene to public health.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Proliferation of mutators in A cell population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Hypermutability and silent mutations in human carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

A simple p53 functional assay for screening cell lines, blood, and tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 mutations isolated in yeast based on loss of transcription factor activity: similarities and differences from p53 mutations detected in human tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Human tumor-derived p53 proteins exhibit binding site selectivity and temperature sensitivity for transactivation in a yeast-based assay.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Conditional gene targeting

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Genome engineering: the new mouse genetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Mutational spectrometry: a general approach for hot-spot point mutations in selectable genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Enhanced restriction site mutation (RSM) analysis of 1,2-dimethylhydrazine induced mutations, using endogenous p53 intron sequences.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Geographic variation of p53 mutational profile in nonmalignant human liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 mutations in cutaneous lesions induced in the hairless mouse by a solar ultraviolet light simulator.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

The role of UV-B light in skin carcinogenesis through the analysis of p53 mutations in squamous cell carcinomas of hairless mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Sunlight and skin cancer: inhibition of p53 mutations in UV-irradiated mouse skin by sunscreens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Chronic ultraviolet exposure-induced p53 gene alterations in Sencar mouse skin carcinogenesis model.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Frequent p53 alterations but low incidence of ras mutations in UV-B-induced skin tumors of hairless mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Role of tumor suppressor genes in transplacental lung carcinogenesis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

K-ras mutations in lung tumors from A/J and A/J×TSG-p53 F1 mice treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and phenethyl isothiocyanate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Characterization of p53 mutations in methylene chloride-induced lung tumors from B6C3F1 mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Dose-dependent ras mutation spectra in N-nitrosodiethylamine induced mouse liver tumors and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced mouse lung tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Induction of mutations in Ki-ras and INK4a in liver tumors of mice exposed in utero to 3-methylcholanthrene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Lack of p53 and ras mutations in Helicobacter hepaticus-induced liver tumors in A/JCr mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Lack of p53 point mutations in chemically induced mouse hepatoblastomas: an end-stage, highly malignant hepatocellular tumor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Screening for p53 mutations in C3H/He mouse liver tumors derived spontaneously or induced with diethylnitrosamine or phenobarbitone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Rare occurrence of ras and p53 gene mutations in mouse stomach tumors induced by N-methyl-N-nitrosourea.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Mutation, loss of heterozygosity, and recombination of the p53 gene in mouse forestomach tumors induced by 2-amino-3,4-dimethylimidazo[4,5-f]quinoline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Induction of hepatocellular carcinoma and highly metastatic squamous cell carcinomas in the forestomach of mice by feeding 2-amino-3,4-dimethylimidazo[4,5-f]quinoline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

LOH and mutational analysis of p53 alleles in mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl) nitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Enhancement of urinary bladder carcinogenesis in nullizygous p53-deficient mice by N-butyl-N-(4-hydroxybutyl)nitrosamine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Clonal analysis of urothelial carcinomas in C3H/HeN<-->BALB/c chimeric mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Frequent p53 mutations and occasional loss of chromosome 4 in invasive bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in B6D2F1 mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Genetic instability and p53 mutations in metastatic foci of mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Frequent mutations of the p53 gene and infrequent H- and K-ras mutations in urinary bladder carcinomas of NON/Shi mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Infrequent p53 mutations in 7,12-dimethylbenz[a]anthracene-induced mammary tumors in BALB/c and p53 hemizygous mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Rare occurrence of p53 and ras gene mutations in preneoplastic and neoplastic mouse endometrial lesions induced by N-methyl-N-nitrosourea and 17 beta-estradiol.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Predominant p53 G-->A transition mutation and enhanced cell proliferation in uterine sarcomas of CBA mice treated with 1,2-dimethylhydrazine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Mutational and LOH analyses of p53 alleles in colon tumors induced by 1,2-dimethylhydrazine in F1 hybrid mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Absence of MDM-2 gene amplification in experimentally induced tumors regardless of p53 status.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 is not inactivated in B6C3F1 mouse vascular tumors arising spontaneously or associated with long-term administration of the thiazolidinedione troglitazone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

p53 gene mutation and loss of heterozygosity of chromosome 11 in methylcholanthrene-induced mouse sarcomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Lessons from the p53 mutant mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2899%2900162-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(99)00162-1

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29 July 2017

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