Proapoptotic p53-interacting protein 53BP2 is induced by UV irradiation but suppressed by p53 (Q24551160)

2

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L H Rohde

3

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T D Perez

4

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D J O'Connor

5

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X Lu

6

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J M Ford

7

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L Naumovski

Molecular and Cellular Biology

8

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language of work or name

English

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publication date

November 2000

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published in

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volume

20

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issue

21

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page(s)

8018-25

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cites work

APCL, a central nervous system-specific homologue of adenomatous polyposis coli tumor suppressor, binds to p53-binding protein 2 and translocates it to the perinucleus

1 reference

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NF-kappaB subunit p65 binds to 53BP2 and inhibits cell death induced by 53BP2

24 March 2017

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Nucleocytoplasmic shuttling of oncoprotein Hdm2 is required for Hdm2-mediated degradation of p53

24 March 2017

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Covalent and noncovalent modifiers of the p53 protein

24 March 2017

1 reference

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Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2

24 March 2017

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Mdm2 promotes the rapid degradation of p53

24 March 2017

1 reference

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Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

24 March 2017

1 reference

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The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

24 March 2017

1 reference

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Two cellular proteins that bind to wild-type but not mutant p53

24 March 2017

1 reference

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Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

24 March 2017

1 reference

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Regulation of p53 stability by Mdm2

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

p53, the cellular gatekeeper for growth and division

24 March 2017

1 reference

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Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines

24 March 2017

1 reference

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Functions of the MDM2 oncoprotein

24 March 2017

1 reference

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p300/MDM2 complexes participate in MDM2-mediated p53 degradation

24 March 2017

1 reference

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Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53

24 March 2017

1 reference

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Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

24 March 2017

1 reference

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Nucleolar Arf sequesters Mdm2 and activates p53

7 April 2017

1 reference

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7 April 2017

p53: puzzle and paradigm

1 reference

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Transcriptional repression by wild-type p53 utilizes histone deacetylases, mediated by interaction with mSin3a.

7 April 2017

1 reference

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Mechanisms of p53-mediated apoptosis

27 September 2017

1 reference

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The dual role model for p53 in maintaining genomic integrity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Nuclear localization of IkappaB alpha is mediated by the second ankyrin repeat: the IkappaB alpha ankyrin repeats define a novel class of cis-acting nuclear import sequences

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

A proline-rich motif in p53 is required for transactivation-independent growth arrest as induced by Gas1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Gas1-induced growth suppression requires a transactivation-independent p53 function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Genomic instability due to germline p53 mutations drives preneoplastic Progression toward cancer in human cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Mediation of c-Myc-induced apoptosis by p53.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Spontaneous abnormalities in normal fibroblasts from patients with Li-Fraumeni cancer syndrome: aneuploidy and immortalization

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86412

RB regulates the stability and the apoptotic function of p53 via MDM2

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11027272

12 December 2020

inferred from PubMed ID database lookup

A matter of life and cell death

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11027272

12 December 2020

inferred from PubMed ID database lookup

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11027272

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/MCB.20.21.8018-8025.2000

0 references

Fatcat ID

release_ghbaur5jyjfdrpvhb6rql3pznu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ghbaur5jyjfdrpvhb6rql3pznu

24 November 2022