p53, the cellular gatekeeper for growth and division (Q27860990)

Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

Europe PubMed Central

title

p53, the cellular gatekeeper for growth and division (English)

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author name string

A J Levine

series ordinal

1

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language of work or name

English

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publication date

7 February 1997

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published in

Cell

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volume

88

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page(s)

323-31

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issue

3

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes.

1 reference

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

1 reference

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7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

1 reference

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7 January 2021

A p53-dependent mouse spindle checkpoint

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Gain of function mutations in p53.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

1 reference

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7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Allosteric activation of latent p53 tetramers

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Activation of p53 sequence-specific DNA binding by short single strands of DNA requires the p53 C-terminus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms

1 reference

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7 January 2021

Growth suppression of Friend virus-transformed erythroleukemia cells by p53 protein is accompanied by hemoglobin production and is sensitive to erythropoietin

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

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https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

A functionally inactive p53 protein in teratocarcinoma cells is activated by either DNA damage or cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

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7 January 2021

A teratologic suppressor role for p53 in benzo[a]pyrene-treated transgenic p53-deficient mice.

1 reference

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Genetic determinants of p53-induced apoptosis and growth arrest

1 reference

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7 January 2021

Essential role for p53-mediated transcription in E1A-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Myc-mediated apoptosis requires wild-type p53 in a manner independent of cell cycle arrest and the ability of p53 to induce p21waf1/cip1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Identification of a novel p53 functional domain that is necessary for efficient growth suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53 modulation of TFIIH-associated nucleotide excision repair activity

1 reference

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7 January 2021

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

p53 and E2F-1 cooperate to mediate apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2981871-1

7 January 2021

Sunburn and p53 in the onset of skin cancer

1 reference

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7 January 2021

10.1016/S0092-8674(00)81871-1

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

565377

565377

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference