C/EBPalpha regulates formation of S-phase-specific E2F-p107 complexes in livers of newborn mice (Q24554514)

Cyclin-dependent kinase 4

1 reference

RB transcriptional corepressor 1

1 reference

CCAAT/enhancer binding protein (C/EBP), alpha

1 reference

Cyclin-dependent kinase 2

1 reference

E2F transcription factor 1

1 reference

Transcription factor Dp 1

1 reference

RB transcriptional corepressor like 2

1 reference

RB transcriptional corepressor like 1

1 reference

Molecular and Cellular Biology

author name string

N A Timchenko

series ordinal

1

0 references

M Wilde

series ordinal

2

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G J Darlington

series ordinal

3

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language of work or name

English

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publication date

April 1999

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published in

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volume

19

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issue

4

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page(s)

2936-45

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cites work

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E2F-4, a new member of the E2F gene family, has oncogenic activity and associates with p107 in vivo

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Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteins

7 April 2017

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CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice

27 September 2017

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Inactivation of the IL-6 gene prevents development of multicentric Castleman's disease in C/EBP beta-deficient mice

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Inhibition of cell proliferation by C/EBP alpha occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen

27 September 2017

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CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program

27 September 2017

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Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter

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Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes

27 September 2017

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27 September 2017

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27 September 2017

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CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein

27 September 2017

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Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-alpha identifies a dominant antiproliferative role for this isoform in hepatocytes

27 September 2017

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The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite

27 September 2017

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27 September 2017

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Role of the CCAAT/enhancer binding protein-alpha transcription factor in the glucocorticoid stimulation of p21waf1/cip1 gene promoter activity in growth-arrested rat hepatoma cells

30 May 2018

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Glucocorticoids stimulate p21 gene expression by targeting multiple transcriptional elements within a steroid responsive region of the p21waf1/cip1 promoter in rat hepatoma cells

30 May 2018

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pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes.

30 May 2018

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Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

30 May 2018

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30 May 2018

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Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A.

30 May 2018

1 reference

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The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F

30 May 2018

1 reference

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A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex.

30 May 2018

1 reference

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Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

30 May 2018

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Essential role of E2F recognition sites in regulation of the proliferating cell nuclear antigen gene promoter during Drosophila development.

28 November 2018

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28 November 2018

Tumor suppressor genes

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12 December 2020

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells

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12 December 2020

Targeted in vivo expression of the cyclin-dependent kinase inhibitor p21 halts hepatocyte cell-cycle progression, postnatal liver development and regeneration

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12 December 2020

Targeted disruption of p107: functional overlap between p107 and Rb

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12 December 2020

p53-independent induction of p21WAF1/CIP1 expression in pericentral hepatocytes following carbon tetrachloride intoxication

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12 December 2020